CYP17A1 — 카탈로그 52건

Gene CYP17A1 NCBI Gene 1586

취급 제조사 7곳

Cusabio Abbexa MyBioSource Biosynth Cloud-Clone ELK Biotechnology Abnova

국내 소싱 가능

52건

유전자 개요

CYP17A1은 약물 대사와 콜레스테롤·스테로이드·지질 합성에 관여하는 시토크롬 P450(cytochrome P450) 슈퍼패밀리(superfamily)에 속하는 단일산소화효소(monooxygenase)를 암호화한다. 이 효소는 소포체(endoplasmic reticulum)에 위치하며 17알파-수산화효소(17alpha-hydroxylase)와 17,20-분해효소(17,20-lyase) 활성을 모두 가져 프로게스틴, 미네랄로코르티코이드, 글루코코르티코이드, 안드로겐, 에스트로겐을 생성하는 스테로이드 생성 경로의 핵심 효소로 작용한다. 유전자 변이는 단독 스테로이드-17알파-수산화효소 결핍, 17알파-수산화효소/17,20-분해효소 결핍, 가성반음양, 부신 과형성(adrenal hyperplasia)과 연관된다.

Androgen biosynthesisDefective CYP17A1 causes AH5Glucocorticoid biosynthesis

congenital adrenal hyperplasia due to 17-alpha-hydroxylase deficiency46,XY disorder of sex development due to isolated 17,20 lyase deficiencycongenital adrenal hyperplasia17,20-lyase deficiency, isolatedprostate canceradrenal gland disease17-alpha-hydroxylase/17,20-lyase deficiency, combined completecombined partial 17-alpha-hydroxylase/17,20-lyase deficiency

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) The diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1). · J Steroid Biochem Mol Biol (2015)A Review on CYP11A1, CYP17A1, and CYP19A1 Polymorphism Studies: Candidate Susceptibility Genes for Polycystic Ovary Syndrome (PCOS) and Infertility. · Genes (Basel) (2022)CYP17A1: a biochemistry, chemistry, and clinical review. · Curr Top Med Chem (2013)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
Cusabio	T094-109967-01	CSB-RA554990A0HU	CYP17A1 Recombinant Monoclonal Antibody	Rabbit	Monoclonal	Human, Rat	ELISA, WB, IHC, IF	50μl, 100μl
Abbexa	F158-117544-01	abx377322	Steroid 17-Alpha Hydroxylase/17,20 Lyase (CYP17A1) Antibody	Rabbit	Polyclonal	Human	ELISA, WB, IHC	50 µg
Abbexa	F158-104809-01	abx111919	Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody	Rabbit	Polyclonal	Human	ELISA, WB, IHC, IF/ICC	100 µl
Abbexa	F158-115128-01	abx324796	Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1) Antibody	Rabbit	Polyclonal	Human	ELISA, WB, IHC, IF/ICC	50 µg
Abbexa	F158-100119-01	abx001208	Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody	Rabbit	Polyclonal	Rat	WB	60 µl
Abbexa	F158-101950-01	abx033739	Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody	Rabbit	Polyclonal	Human	ELISA, WB, IF/ICC	80 µl
Abbexa	F158-110842-01	abx232145	Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody	Rabbit	Polyclonal	Human	ELISA, WB, IHC, IF/ICC	100 µg
Abbexa	F158-119701-01	abx432567	Steroid 17-Alpha-Hydroxylase/17,20 Lyase (CYP17A1) Antibody	Goat	Polyclonal	Human	ELISA, WB, IHC	200 µl
Cusabio	T094-105245-01	CSB-MA905936	CYP17A1 Monoclonal Antibody	Mouse	Monoclonal	Human	ELISA,WB	100μl
MyBioSource	R247-213543-01	MBS9607055	CYP17A1, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	WB; IHC; IF; ICC; ELISA	0.1 mL
Biosynth	F502-119589-01	70R-16703	CYP17A1 antibody	Rabbit	Polyclonal	Human; Cross: Human	ELISA, IHC, IF, WB	50 ul
Biosynth	F502-104283-01	10R-3774	CYP17A1 antibody	Mouse	Monoclonal	Human; Cross: Human	WB	100 ul
Biosynth	F502-104282-01	10R-3773	CYP17A1 antibody	Mouse	Monoclonal	Human; Cross: Human	WB	100 ul
Biosynth	F502-127974-01	70R-32397	CYP17A1 antibody	Rabbit	Polyclonal	CYP17A1 antibody detects endogenous levels of total Cytochrome P450 17A1 protein	WB, ELISA	0.1 mg
Cloud-Clone	T813-122902-01	PAC016Hu01	Polyclonal Antibody to Cytochrome P450 17A1 (CYP17A1)	Rabbit	Polyclonal	Human	WB; ICC/IF	100µl
Cloud-Clone	T813-122904-01	PAC016Ra01	Polyclonal Antibody to Cytochrome P450 17A1 (CYP17A1)	Rabbit	Polyclonal	Rat	WB; IHC	100µl
Cloud-Clone	T813-122903-01	PAC016Mu01	Polyclonal Antibody to Cytochrome P450 17A1 (CYP17A1)	Rabbit	Polyclonal	Murine	WB; IHC	100µl
MyBioSource	R247-171490-01	MBS7000627	Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1), Polyclonal Antibody	Rabbit	Polyclonal	Human	ELISA; WB; IHC	0.05 mg
ELK Biotechnology	T376-120295-01	ES4948	CYP17A1 rabbit pAb	Rabbit	Polyclonal	Human	WB;IHC;IF;ELISA	50μL

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
MyBioSource	R247-133204-01	MBS2127266	Cytochrome P450 17A1 (CYP17A1), ELISA Kit	Human	ELISA	Human tissue homogenates, cell lysates and other biological fluids	< 0.054ng/mL	24-Strip-Wells
MyBioSource	R247-181741-01	MBS7238766	Steroid 17 Alpha hydroxylase/17, 20 lyase (CYP17A1), ELISA Kit	Human	ELISA	Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate	0.1ng/mL	48-Strip-Wells
MyBioSource	R247-144520-01	MBS2884521	Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1), ELISA Kit	Human	ELISA		0.156 mmol/L	48-Strip-Wells
MyBioSource	R247-182239-01	MBS7246853	Steroid 17-Alpha hydroxylase/17, 20 lyase (CYP17A1), ELISA Kit	Rat	ELISA	Serum, Plasma, Cell Culture Supernatants, Body Fluid And Tissue Homogenate	0.1 ng/mL.	48-Strip-Wells
MyBioSource	R247-181437-01	MBS7234138	Steroid 17-alpha-hydroxylase/17, 20 lyase (CYP17A1), ELISA Kit	Mouse	ELISA	Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate	0.1 ng/mL.	48-Strip-Wells
MyBioSource	R247-203042-01	MBS9305272	Steroid 17-alpha-hydroxylase/17, 20 lyase;Cytochrome P450 17A1, CYP17A1, ELISA Kit	Porcine	ELISA		1.0ng/ml	48-Strip-Wells
Cloud-Clone	T813-146239-01	SEC016Mu	ELISA Kit for Cytochrome P450 17A1 (CYP17A1)	Murine	ELISA	Tissue homogenates, cell lysates and other biological fluids	0.62ng/mL.	96T
MyBioSource	R247-143194-01	MBS280443	Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1), ELISA Kit	Horse	ELISA	Serum, Plasma, Other biological fluids		48 Tests
MyBioSource	R247-148847-01	MBS3809832	Cytochrome P450C17 (CYP17A1), ELISA Kit	Rat	ELISA	Serum, plasma, cell culture supernate and other biological fluids	10 pg/ml	48-Strip-Wells
MyBioSource	R247-148475-01	MBS3803862	Cytochrome P450c17 (CYP17A1), ELISA Kit	Human	ELISA	Serum, plasma, cell culture supernate and other biological fluids	10 pg/ml	48-Strip-Wells
MyBioSource	R247-143220-01	MBS280481	Steroid 17-alpha-hydroxylase/17,20 (CYP17A1), ELISA Kit	Sheep	ELISA	Serum, Plasma, Other biological fluids		48 Tests
MyBioSource	R247-182267-01	MBS7247245	Steroid 17-alpha-hydroxylase/17, 20 lyase (CYP17A1), ELISA Kit	Rabbit	ELISA	Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate		48-Strip-Wells
MyBioSource	R247-180828-01	MBS7224344	Steroid 17-alpha-hydroxylase/17, 20 lyase (CYP17A1), ELISA Kit	Bovine	ELISA	Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate		48-Strip-Wells
MyBioSource	R247-179489-01	MBS7201388	Steroid 17-alpha-hydroxylase/17, 20 lyase (CYP17A1), ELISA Kit	Porcine	ELISA	Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate		48-Strip-Wells
MyBioSource	R247-181959-01	MBS7242083	Steroid 17-alpha-hydroxylase/17, 20 lyase (CYP17A1), ELISA Kit	Chicken	ELISA	Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate		48-Strip-Wells
MyBioSource	R247-182522-01	MBS7251640	Steroid 17-alpha-hydroxylase/17, 20 lyase (CYP17A1), ELISA Kit	Guinea Pig	ELISA	Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate		48-Strip-Wells
MyBioSource	R247-180286-01	MBS7214650	Steroid 17-alpha-hydroxylase/17, 20 lyase (CYP17A1), ELISA Kit	Monkey	ELISA	Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate		48-Strip-Wells
MyBioSource	R247-181575-01	MBS7236078	Steroid 17-alpha-hydroxylase/17, 20 lyase (CYP17A1), ELISA Kit	Sheep	ELISA	Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate		48-Strip-Wells
MyBioSource	R247-144557-01	MBS2884790	Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1), ELISA Kit	Bovine	ELISA			48-Strip-Wells
MyBioSource	R247-144223-01	MBS2882293	Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1), ELISA Kit	Pig	ELISA			48-Strip-Wells
MyBioSource	R247-204088-01	MBS9329553	cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), ELISA Kit	Pig	ELISA			48-Strip-Wells
MyBioSource	R247-203040-01	MBS9305247	Steroid 17-alpha-hydroxylase/17, 20 lyase;Cytochrome P450 17A1, CYP17A1, ELISA Kit	Rat	ELISA			48-Strip-Wells
MyBioSource	R247-203055-01	MBS9305683	Steroid 17-alpha-hydroxylase/17, 20 lyase;Cytochrome P450 17A1, CYP17A1, ELISA Kit	Mouse	ELISA			48-Strip-Wells
MyBioSource	R247-144783-01	MBS2886698	Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1), ELISA Kit	Chicken	ELISA			48-Strip-Wells
MyBioSource	R247-203054-01	MBS9305673	Steroid 17-alpha-hydroxylase/17, 20 lyase;Cytochrome P450 17A1, CYP17A1, ELISA Kit	Bovine	ELISA			48-Strip-Wells
MyBioSource	R247-203039-01	MBS9305177	Steroid 17-alpha-hydroxylase/17, 20 lyase;Cytochrome P450 17A1, CYP17A1, ELISA Kit	Chicken	ELISA
MyBioSource	R247-203386-01	MBS9317164	cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), ELISA Kit	Goat	ELISA

제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
Abbexa	F158-123804-01	abx656747	Human Steroid 17-Alpha-Hydroxylase / 17,20 Lyase (CYP17A1) Protein	E. coli	Human	WB, SDS-PAGE	50 µg
Cloud-Clone	T813-135273-01	RPC016Mu01	Recombinant Cytochrome P450 17A1 (CYP17A1)	E.coli	Murine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-135272-01	RPC016Hu01	Recombinant Cytochrome P450 17A1 (CYP17A1)	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-135274-01	RPC016Ra01	Recombinant Cytochrome P450 17A1 (CYP17A1)	E.coli	Rat	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
MyBioSource	R247-176023-01	MBS7110835	Steroid 17-alpha-hydroxylase/17, 20 lyase (CYP17A1), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell			0.02 mg
Abnova	U731-100308-01	H00001586-P01	CYP17A1 (Human) Recombinant Protein (P01)	Wheat Germ (in vitro)	Human	AP,Array,ELISA,WB-Re

CYP17A1 — 카탈로그 52건

유전자 개요

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