CTBP2 — 카탈로그 50건
Gene CTBP2
NCBI Gene 1488
취급 제조사 4곳
국내 소싱 가능
50건
유전자 개요
CTBP2는 대체 전사체(alternative transcripts)를 통해 서로 다른 두 단백질을 암호화하며, 하나는 전사 억제인자(transcriptional repressor)이고 다른 아이소폼(isoform)은 시냅스 리본(synaptic ribbons)이라 불리는 특수 시냅스의 주요 구성 요소이다. 두 단백질 모두 NAD+ 의존성 2-하이드록시산 탈수소효소(NAD+-dependent 2-hydroxyacid dehydrogenases)와 유사한 NAD+ 결합 도메인(NAD+ binding domain)을 지닌다.
Negative Regulation of CDH1 Gene TranscriptionRepression of WNT target genesSensory processing of sound by inner hair cells of the cochleaSignaling by TCF7L2 mutants
hearing lossPulmonary artery atresiaSensorineural hearing impairmentplatelet counthearing process qualityage-related hearing impairmentprostate carcinomaerythrocyte count
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) An ARF/CtBP2 complex regulates BH3-only gene expression and p53-independent apoptosis. · Cell Death Differ (2010)The CTBP2-PCIF1 complex regulates m6Am modification of mRNA in head and neck squamous cell carcinoma. · J Clin Invest (2023)Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity. · J Biol Chem (2023)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Biosynth | F502-127300-01 | 70R-31783 | CtBP2 antibody | Rabbit | Polyclonal | CtBP2 antibody detects endogenous levels of total CtBP2 protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-117413-01 | 70R-14092 | CtBP2 antibody | Rabbit | Polyclonal | Human | WB, IHC-P, IHC-F, ICC | 0.1 mg | |
| Biosynth | F502-115994-01 | 70R-12678 | CtBP2 antibody | Rabbit | Polyclonal | Human | IF, ICC, WB | 100 ul | |
| Biosynth | F502-119522-01 | 70R-16641 | CTBP2 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| Cloud-Clone | T813-126328-01 | PAF359Hu01 | Polyclonal Antibody to C-Terminal Binding Protein 2 (CTBP2) | Rabbit | Polyclonal | Human | WB | 100µl | |
| Cloud-Clone | T813-114959-01 | MAF359Hu21 | Monoclonal Antibody to C-Terminal Binding Protein 2 (CTBP2) | Mouse | Monoclonal | Human | WB | 100µl | |
| Biosynth | F502-136059-01 | 70R-51511 | CTBP2 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of CTBP2 protein; Cross: Mouse, Rat, Bovine | WB, IHC, IF, ICC | 100 ul |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
CTBP1
Signaling by TCF7L2 mutants
HDAC1
Repression of WNT target genes
MYC
Repression of WNT target genes
AXIN2
Repression of WNT target genes
ACTB
Sensory processing of sound by inner hair cells of the cochlea
SYP
Sensory processing of sound by inner hair cells of the cochlea
RAB3A
Sensory processing of sound by inner hair cells of the cochlea
SNAP25
Sensory processing of sound by inner hair cells of the cochlea