취급 제조사 2곳
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30건
유전자 개요
이 유전자는 Ser/Thr 단백질 키나아제(kinase) 계열에 속하는 단백질을 암호화한다. 이 단백질은 DNA 손상이나 복제되지 않은 DNA 존재 시 점검관(checkpoint) 매개 세포 주기(cell cycle) 정지에 필수적이다. 또한 감수 1기 전기에 염색질(chromatin)에 결합하는 두 세포 주기 단백질인 ATM과 ATR로부터 신호를 통합하는 역할을 한다. 이 단백질에 의한 CDC25A 단백질 인산가수분해효소(phosphatase)의 인산화(phosphorylation)는 이중 가닥 DNA 파괴 시 세포 주기의 진행 지연에 필요하다. 이 유전자에는 여러 대체 스플라이싱 전사 변이체가 발견되었다.
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- 대표 논문 (PubMed) Roles of Chk1 in cell biology and cancer therapy. · Int J Cancer (2014)ATR/CHK1 inhibitors and cancer therapy. · Radiother Oncol (2018)Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach. · J Biol Chem (2002)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| MyBioSource | R247-212411-01 | MBS9601670 | CHK1, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| Biosynth | F502-128749-01 | 70R-33504 | Chk1 antibody (Ser301) | Rabbit | Polyclonal | Chk1 antibody detects endogenous levels of Chk1 only when phosphorylated at serine 301 | WB, IF, ELISA | 0.1 mg | |
| Biosynth | F502-130574-01 | 70R-35358 | Chk1 antibody | Rabbit | Polyclonal | Chk1 Antibody detects endogenous levels of total Chk1 protein | WB, ELISA | 0.1 mg | |
| Biosynth | F502-133903-01 | 70R-49544 | CHK1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of CHK1 protein; Cross: Mouse, Rat | WB | 100 ul | |
| Biosynth | F502-133904-01 | 70R-49545 | CHK1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of CHK1 protein; Cross: Mouse, Rat | WB, IHC, IF, ICC | 100 ul | |
| Biosynth | F502-132106-01 | 70R-37201 | Chk1 antibody (Ser345) | Rabbit | Polyclonal | Chk1 antibody (Ser345) detects endogenous levels of Chk1 only when phosphorylated at serine 345. The antibody will detect species specific phosphorylation as follows: Human: Ser345, Mouse: Ser345, Rat: Ser345; Cross: Mouse, Rat | IHC | 0.1 mg | |
| Biosynth | F502-133905-01 | 70R-49546 | CHK1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of CHK1 protein; Cross: Mouse, Rat | WB, IHC, IF, ICC | 100 ul | |
| Biosynth | F502-132349-01 | 70R-37427 | CHK1 antibody (Ser317) | Rabbit | Polyclonal | Human; Cross: Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-133901-01 | 70R-49542 | CHK1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of CHK1 protein; Cross: Mouse, Rat | WB | 100 ul | |
| Biosynth | F502-131129-01 | 70R-36011 | Chk1 antibody | Rabbit | Polyclonal | Chk1 antibody detects endogenous levels of Chk1 only when phosphorylated at Serine 317; Cross: Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-128747-01 | 70R-33502 | Chk1 antibody (Ser286) | Rabbit | Polyclonal | Chk1 antibody detects endogenous levels of Chk1 only when phosphorylated at serine 286 | WB, IF, ELISA | 0.1 mg | |
| Biosynth | F502-132485-01 | 70R-37553 | Chk1 antibody | Rabbit | Polyclonal | Human; Cross: Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-128750-01 | 70R-33505 | Chk1 antibody | Rabbit | Polyclonal | Chk1 antibody detects endogenous levels of total Chk1 protein; Cross: Mouse, Rat | IF, ELISA | 0.1 mg | |
| Biosynth | F502-131914-01 | 70R-37000 | Chk1 antibody | Rabbit | Polyclonal | Chk1 antibody detects endogenous levels of Chk1 protein around serine 317; Cross: Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-132484-01 | 70R-37552 | Chk1 antibody | Rabbit | Polyclonal | Human | WB | 0.1 mg | |
| Biosynth | F502-130613-01 | 70R-35412 | Chk1 antibody (Ser280) | Rabbit | Polyclonal | Human, Mouse, Rat; Cross: Mouse, Rat. Specific detection of phosphorylated Human: Ser280, Mouse: Ser280, Rat: Ser280 | WB, ELISA | 0.1 mg | |
| Biosynth | F502-132125-01 | 70R-37219 | CHK1 antibody (Ser280) | Rabbit | Polyclonal | CHK1 antibody (Ser280) detects endogenous levels of CHK1 only when phosphorylated at serine 280 | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-128748-01 | 70R-33503 | Chk1 antibody | Rabbit | Polyclonal | Chk1 antibody detects endogenous levels of total Chk1 protein; Cross: Mouse, Rat | WB, IF, ELISA | 0.1 mg | |
| Biosynth | F502-133906-01 | 70R-49547 | CHK1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of CHK1 protein | WB, IHC, IF, ICC | 100 ul | |
| Biosynth | F502-133902-01 | 70R-49543 | CHK1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of CHK1 protein; Cross: Mouse, Rat | WB, IHC | 100 ul | |
| Biosynth | F502-130590-01 | 70R-35375 | Chk1 antibody (Ser296) | Rabbit | Polyclonal | Human; Cross: Human. Specific detection of phosphorylated Human: Ser296 | WB, IHC | 0.1 mg | |
| Biosynth | F502-131791-01 | 70R-36841 | Chk1 antibody | Rabbit | Polyclonal | Chk1 antibody detects endogenous levels of total Chk1 protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-131068-01 | 70R-35944 | Chk1 antibody (Ser345) | Rabbit | Polyclonal | Human, Mouse, Rat; Cross: Mouse, Rat - Reactive with proteins phosphorylated as follows: Human: Ser345, Mouse: Ser345, Rat: Ser345 | IHC, ELISA | 0.1 mg | |
| Biosynth | F502-103194-01 | 10R-1796 | CHK1 antibody | Mouse | Monoclonal | Human, Mouse | ELISA, WB | 100 ul | |
| Biosynth | F502-130585-01 | 70R-35370 | Chk1 antibody | Rabbit | Polyclonal | Chk1 antibody detects endogenous levels of total Chk1 protein | IHC, ELISA | 0.1 mg | |
| Biosynth | F502-124798-01 | 70R-21482 | CHK1 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| MyBioSource | R247-122541-01 | MBS1750555 | Chk1, Polyclonal Antibody | Rabbit | Polyclonal | Human | WB | 0.01 mg | |
| MyBioSource | R247-188640-01 | MBS767885 | Chk1, Monoclonal Antibody | Mouse | Monoclonal | Human, Mouse, Rat | ELISA; WB; IHC | 0.1 mg | |
| Biosynth | F502-108808-01 | 20R-1994 | Chk1 antibody | Rabbit | Human; Cross: Human | WB | 0.05 mg | ||
| Biosynth | F502-109097-01 | 20R-2292 | Chk1 antibody | Rabbit | Human; Cross: Human, Mouse | IHC, WB | 0.05 mg |