CDK7 — 카탈로그 27건
Gene CDK7
NCBI Gene 1022
취급 제조사 3곳
국내 소싱 가능
27건
유전자 개요
이 유전자가 지정하는 단백질은 사이클린 의존성 단백질 키나아제(CDK) 계열의 구성원입니다. CDK 계열 구성원들은 효모 Saccharomyces cerevisiae의 cdc28 및 Schizosaccharomyces pombe의 cdc2 유전자 산물과 매우 유사하며, 세포 주기 진행의 중요한 조절자로 알려져 있습니다. 이 단백질은 사이클린 H 및 MAT1과 함께 삼량체 복합체를 형성하며, 이는 Cdk-활성화 키나아제(CAK)로 기능합니다. 또한, 전사 개시 및 DNA 복구에 관여하는 전사인자(transcription factor) TFIIH의 필수 구성 요소입니다. 이 단백질은 전사 및 세포 주기 조절 사이의 직접적인 연결고리 역할을 하는 것으로 여겨집니다.
Cyclin A/B1/B2 associated events during G2/M transitionCyclin A:Cdk2-associated events at S phase entryCyclin D associated events in G1Cyclin E associated events during G1/S transition Dual incision in TC-NERFormation of HIV elongation complex in the absence of HIV TatFormation of HIV-1 elongation complex containing HIV-1 TatFormation of Incision Complex in GG-NERFormation of RNA Pol II elongation complex Formation of TC-NER Pre-Incision Complex
HIV infectionneurodegenerative diseaseneutrophil countcardiovascular measurementhypertensionglomerular filtration rateserum creatinine amountblood protein amount
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Cyclin-dependent kinases. · Genome Biol (2014)Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma. · Cancer Cell (2017)CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer. · Cancer Cell (2020)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| MyBioSource | R247-213588-01 | MBS9607215 | CDK7, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| Biosynth | F502-106746-01 | 10R-7840 | CDK7 antibody | Mouse | Monoclonal | Human | WB, IHC-F, ICC | 0.1 mg | |
| Biosynth | F502-128740-01 | 70R-33496 | CDK7 antibody | Rabbit | Polyclonal | CDK7 antibody detects endogenous levels of total CDC25B protein | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-115378-01 | 70R-10469 | CDK7 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig | IHC, WB | 100 ul | |
| Biosynth | F502-103673-01 | 10R-2365 | Cdk7 antibody | Mouse | Monoclonal | Human; Cross: Mouse | IHC, WB | 0.05 mg | |
| Biosynth | F502-133882-01 | 70R-49525 | CDK7 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of CDK7 protein | WB, IHC | 100 ul | |
| Biosynth | F502-128741-01 | 70R-33497 | CDK7 antibody (Thr170) | Rabbit | Polyclonal | CDK7 antibody detects endogenous levels of CDK7 only when phosphorylated at threonine 170; Cross: Mouse | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-119185-01 | 70R-16330 | CDK7 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA | 50 ul | |
| Biosynth | F502-128742-01 | 70R-33498 | CDK7 antibody | Rabbit | Polyclonal | CDK7 antibody detects endogenous levels of total CDK7 protein; Cross: Mouse | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-126216-01 | 70R-30787 | CDK7 antibody | Rabbit | Polyclonal | CDK7 antibody detects endogenous levels of total CDK7 protein; Cross: Mouse | WB, IHC, ELISA | 0.1 mg | |
| Cloud-Clone | T813-122492-01 | PAB880Mu01 | Polyclonal Antibody to Cyclin Dependent Kinase 7 (CDK7) | Rabbit | Polyclonal | Murine | WB; ICC/IF | 100µl | |
| Cloud-Clone | T813-113548-01 | MAB880Hu22 | Monoclonal Antibody to Cyclin Dependent Kinase 7 (CDK7) | Mouse | Monoclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-122491-01 | PAB880Hu01 | Polyclonal Antibody to Cyclin Dependent Kinase 7 (CDK7) | Rabbit | Polyclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| MyBioSource | R247-159345-01 | MBS601240 | cdk7, Monoclonal Antibody | Mouse | Monoclonal | Human, Mouse | WB; IP; IHC; FC/FACS; IF | 0.05 mg | |
| MyBioSource | R247-158815-01 | MBS600532 | cdk7, Monoclonal Antibody | Mouse | Monoclonal | Human, Rat | WB; IP; IHC; ICC | 0.1 mL | |
| MyBioSource | R247-159624-01 | MBS603411 | cdk7, p42, Monoclonal Antibody | Mouse | Monoclonal | Human | WB; IP; IHC | 0.1 mg | |
| MyBioSource | R247-208453-01 | MBS9413651 | CDK7, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; IHC | 0.05 mL | |
| MyBioSource | R247-214421-01 | MBS9611103 | CDK7, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rabbit, Bovine, Dog, Pig, Sheep, Chicken, Zebrafish, Horse | WB; EIA | 0.05 mL | |
| MyBioSource | R247-214330-01 | MBS9610677 | CDK7, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Rabbit, Bovine, Dog, Pig, Sheep, Chicken, Zebrafish, Horse | WB; IHC; EIA | 0.05 mL | |
| MyBioSource | R247-159674-01 | MBS603967 | cdk7, Monoclonal Antibody | Mouse | Monoclonal | Human | WB; IP; ICC; FC/FACS | 0.05 mg | |
| MyBioSource | R247-159622-01 | MBS603392 | cdk7, Monoclonal Antibody | Mouse | Monoclonal | Recognizes cdk7 (Cyclin-dependent Kinase 7). | ELISA; WB | 0.15 mg | |
| MyBioSource | R247-159976-01 | MBS609706 | CDK7, Monoclonal Antibody | Mouse | Monoclonal | Human | WB; IHC; ICC; IF | 0.1 mg | |
| Biosynth | F502-108590-01 | 20R-1296 | CDK7 antibody | Rabbit | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig | IHC, WB | 100 ul | ||
| MyBioSource | R247-149705-01 | MBS395246 | Cyclin Dependant Kinase 7 (CDK7), Monoclonal Antibody | Mouse | Monoclonal | Human | WB; IP; IHC | 0.1 mg |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
GTF2H4
RNA Pol II CTD phosphorylation and interaction with CE
GTF2F1
RNA Pol II CTD phosphorylation and interaction with CE
TBP
RNA Polymerase I Transcription Termination
TAF4
RNA Polymerase II Promoter Escape
CDK9
Tat-mediated elongation of the HIV-1 transcript
SUPT16H
Tat-mediated elongation of the HIV-1 transcript
CDK2
Cyclin E associated events during G1/S transition UBB
Transcription-Coupled Nucleotide Excision Repair (TC-NER)