CDC25C — 카탈로그 17건
Gene CDC25C
NCBI Gene 995
취급 제조사 3곳
국내 소싱 가능
17건
유전자 개요
이 유전자는 세포 분열 조절에 중요한 역할을 하는 보존된 단백질을 암호화한다. 이 단백질은 사이클린 B(cyclin B)-결합 CDC2의 탈인산화를 지시하여 유사분열(mitosis) 진입을 유발한다. 또한, p53에 의한 성장 정지를 억제한다. 이 유전자에는 여러 대체 스플라이싱 전사 변이체들이 기술되어 있다.
Activation of ATR in response to replication stressChk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complexCyclin A/B1/B2 associated events during G2/M transitionDeregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease modelsPolo-like kinase mediated eventsRHO GTPases activate PKNsTP53 Regulates Transcription of Genes Involved in G2 Cell Cycle ArrestTP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
body weightAlzheimer diseasepotassium measurementbody mass indexbody heightmorbid obesitysleep duration traitlymphocyte count
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C. · Curr Opin Cell Biol (2000)C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding. · Cell Growth Differ (1998)The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase. · Cell Signal (2000)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-109382-01 | CSB-RA004996A0HU | CDC25C Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human | ELISA, WB, IHC, IF | 50μl, 100μl | |
| MyBioSource | R247-213584-01 | MBS9607202 | CDC25C, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| Biosynth | F502-132102-01 | 70R-37198 | cdc25C antibody (Ser216) | Rabbit | Polyclonal | Human | IHC, IF | 0.1 mg | |
| Biosynth | F502-130387-01 | 70R-35138 | CDC25C antibody | Rabbit | Polyclonal | CDC25C antibody detects endogenous levels of total CDC25C protein | IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-130306-01 | 70R-35030 | CDC25C antibody (Thr48) | Rabbit | Polyclonal | Human, Mouse; Cross: Mouse. Specific detection of phosphorylated Human: Thr48, Mouse: Thr48 | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-115387-01 | 70R-10478 | CDC25C antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rabbit | WB | 100 ul | |
| Biosynth | F502-103560-01 | 10R-2177 | Cdc25C antibody | Mouse | Monoclonal | Human; Cross: Human | ELISA, WB | 100 ul | |
| Biosynth | F502-106742-01 | 10R-7836 | CDC25C antibody | Mouse | Monoclonal | Human | WB | 0.1 mg | |
| Biosynth | F502-132518-01 | 70R-37583 | CDC25C antibody | Rabbit | Polyclonal | Human | IHC, WB, IF | 0.1 mg | |
| Biosynth | F502-131401-01 | 70R-36359 | CDC25C antibody | Rabbit | Polyclonal | CDC25C antibody detects endogenous levels of total CDC25C protein | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-130424-01 | 70R-35186 | CDC25C antibody (Ser216) | Rabbit | Polyclonal | Human; Cross: Human. Specific detection of phosphorylated Human: Ser216 | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-119149-01 | 70R-16298 | CDC25C antibody | Rabbit | Polyclonal | Human; Cross: Human | ELISA, WB | 50 ul | |
| Biosynth | F502-129816-01 | 70R-34480 | CDC25C antibody (Ser198) | Rabbit | Polyclonal | CDC25C antibody detects endogenous levels of CDC25C only when phosphorylated at serine 198 | IHC, ELISA | 0.1 mg | |
| MyBioSource | R247-122917-01 | MBS1753429 | Cdc25c, Polyclonal Antibody | Rabbit | Polyclonal | Mouse, Rat | WB; EIA | 0.01 mg | |
| Biosynth | F502-109124-01 | 20R-2319 | CDC25C antibody | Rabbit | Human; Cross: Human | IF, IHC, WB | 0.05 mg | ||
| Biosynth | F502-108790-01 | 20R-1975 | CDC25C antibody | Rabbit | Human; Cross: Human | IF, IHC, WB | 0.05 mg | ||
| Biosynth | F502-136030-01 | 70R-51485 | CDC25C antibody | Rabbit | Polyclonal | Recognizes endogenous levels of CDC25C protein; Cross: Mouse, Rat | WB, IHC, IF, ICC | 100 ul |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
CCNB1
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
CDC25A
Polo-like kinase mediated events
SFN
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
CDK1
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
YWHAE
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
EP300
Polo-like kinase mediated events
TP53
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
YWHAZ
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex