CDC25B — 카탈로그 15건
Gene CDC25B
NCBI Gene 994
국내 소싱 가능
15건
유전자 개요
이 유전자는 포스파타아제(phosphatase)의 CDC25 계열 구성원이다. CDC25B는 두 개의 인산기를 제거하여 사이클린 의존성 키나아제(cyclin dependent kinase)인 CDC2를 활성화하며, 유사분열(mitosis) 진입에 필요하다. 세포핵 국소화 및 핵 수출 신호로 인해 세포핵과 세포질(cytoplasm) 사이를 왕래한다. 단백질은 세포 주기(cell cycle)의 M기와 G1기에는 세포핵에 존재하며 S기와 G2기에는 세포질로 이동한다. 종양(tumor) 형성에서의 역할은 아직 규명되지 않았으나, 종양성(oncogenic) 특성을 가진다.
Cyclin A/B1/B2 associated events during G2/M transitionCyclin A:Cdk2-associated events at S phase entryDeregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease modelsRegulation of MITF-M-dependent genes involved in cell cycle and proliferation
Alzheimer diseaselean body massneurodegenerative diseaseerythrocyte volumemean reticulocyte volumebody composition measurementlysosomal storage diseaseParkinson disease
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Cell cycle control by the CDC25 phosphatases. · Anticancer Agents Med Chem (2008)Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation. · Oncogene (2002)Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase. · Oncogene (2000)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-109381-01 | CSB-RA004995A0HU | CDC25B Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human | ELISA | 50μl, 100μl | |
| Biosynth | F502-126082-01 | 70R-30664 | CDC25B antibody (Ser323) | Rabbit | Polyclonal | CDC25B antibody detects endogenous levels of CDC25B only when phosphorylated at serine 323; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-117405-01 | 70R-14084 | CDC25B antibody | Rabbit | Polyclonal | Human | WB, IHC-P | 0.1 mg | |
| Biosynth | F502-128739-01 | 70R-33495 | CDC25B antibody (Ser353) | Rabbit | Polyclonal | CDC25B antibody detects endogenous levels of CDC25B only when phosphorylated at serine 353 | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-119148-01 | 70R-16297 | CDC25B antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, WB | 50 ul | |
| Biosynth | F502-115394-01 | 70R-10484 | CDC25B antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Dog, Guinea Pig, Horse, Pig, Rabbit | IHC, WB | 100 ul | |
| Biosynth | F502-126083-01 | 70R-30665 | CDC25B antibody | Rabbit | Polyclonal | CDC25B antibody detects endogenous levels of total CDC25B protein; Cross: Mouse, Rat | WB, IF, ELISA | 0.1 mg | |
| Cloud-Clone | T813-128462-01 | PAQ124Hu01 | Polyclonal Antibody to Cell Division Cycle Protein 25B (CDC25B) | Rabbit | Polyclonal | Human | WB | 100µl | |
| MyBioSource | R247-212278-01 | MBS9601027 | CDC25B, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| Biosynth | F502-108992-01 | 20R-2179 | Cdc25B antibody | Rabbit | Mouse, Rat | WB | 0.05 mg | ||
| Biosynth | F502-136721-01 | 70R-5503 | CDC25B antibody | Rabbit | Polyclonal | Human,Dog | WB, IHC | 100 ul | |
| Biosynth | F502-136029-01 | 70R-51484 | CDC25B antibody | Rabbit | Polyclonal | Recognizes endogenous levels of CDC25B protein; Cross: Mouse, Rat, Monkey | WB, IF, ICC | 100 ul | |
| ELK Biotechnology | T376-121531-01 | ES8138 | Cdc25B rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | WB;IF;ELISA | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
CDK2
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
CDC25A
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
CDKN1A
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
PLK1
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
CCNB1
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
CDC25C
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
CDK7
Cyclin A:Cdk2-associated events at S phase entry
MET
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation