CD70 — 카탈로그 17건
Gene CD70
NCBI Gene 970
국내 소싱 가능
17건
유전자 개요
이 유전자가 지정하는 단백질은 종양 괴사 인자(TNF) 리간드 계열에 속하는 사이토카인이다. 이 사이토카인은 TNFRSF27/CD27의 리간드이다. 활성화된 T 세포와 B 림프구 표면의 항원으로 작용하며, 휴지기 상태의 림프구에는 나타나지 않는다. 또한, 공동 자극된 T 세포의 증식을 유도하고, 세포 독성 T 세포 생성을 강화하며, T 세포 활성화에 기여한다.
TNFs bind their physiological receptors
severe combined immunodeficiency due to CD70 deficiencyCombined immunodeficiencycombined immunodeficiencylymphoproliferative syndromehematopoietic and lymphoid cell neoplasmnon-Hodgkins lymphomaneurodegenerative diseasegenetic disorder
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity. · Blood (2021)CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma. · Cancer Discov (2024)Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia. · Cancer Cell (2022)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-109371-01 | CSB-RA004954MA1HU | CD70 Recombinant Monoclonal Antibody | Human | Monoclonal | Human | ELISA | 50μl, 100μl | |
| Biosynth | F502-113413-01 | 61R-1271 | CD70 antibody (PE) | Rat | Polyclonal | Mouse | FC | 0.05 mg, 0.1 mg | |
| Biosynth | F502-114452-01 | 61R-CD70PE | CD70 antibody (PE) | Mouse | Polyclonal | Human; Cross: To be determined by end-user | ELISA, FC, ICC, IHC | 120 piece | |
| Biosynth | F502-114451-01 | 61R-CD70FT | CD70 antibody (FITC) | Mouse | Polyclonal | Human; Cross: To be determined by end-user | ELISA, FC, ICC, IHC | 120 piece | |
| Biosynth | F502-106181-01 | 10R-6434 | CD70 antibody | Rat | Monoclonal | Mouse | FC, IHC | 0.05 mg, 0.1 mg | |
| Biosynth | F502-116537-01 | 70R-13191 | CD70 antibody | Rabbit | Polyclonal | Human | WB | 100 ul | |
| Biosynth | F502-115188-01 | 70R-10290 | CD70 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Cow, Guinea Pig, Horse, Rabbit | WB | 100 ul | |
| Biosynth | F502-107353-01 | 10R-CD70BHU | CD70 antibody | Mouse | Monoclonal | Human; Cross: To be determined by end-user | ELISA, FC, ICC, IHC | 0.1 mg | |
| Biosynth | F502-107354-01 | 10R-CD70BHUP | CD70 antibody (Preservative Free) | Mouse | Monoclonal | Human; Cross: To be determined by end-user | ELISA, FC, ICC, IHC | 0.1 mg | |
| Biosynth | F502-133862-01 | 70R-49507 | CD70 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of CD70 protein | WB, IP | 100 ul | |
| MyBioSource | R247-213638-01 | MBS9607422 | CD70, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| MyBioSource | R247-148177-01 | MBS378124 | CD70, Monoclonal Antibody | Rat | Monoclonal | Mouse | BL; FC/FACS | 0.5 mg | |
| ELK Biotechnology | T376-118690-01 | ES1915 | CD70 rabbit pAb | Rabbit | Polyclonal | Human;Rat;Mouse; | WB;ELISA | 50μL | |
| MyBioSource | R247-155465-01 | MBS520620 | CD70, Monoclonal Antibody | Mouse | Monoclonal | Human | IHC | 0.05 mg |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
TNFSF4
TNFs bind their physiological receptors
LTA
TNFs bind their physiological receptors
TNFRSF9
TNFs bind their physiological receptors
TNFRSF1B
TNFs bind their physiological receptors
TNFRSF4
TNFs bind their physiological receptors
TNFSF15
TNFs bind their physiological receptors
TNFSF13
TNFs bind their physiological receptors
EDA
TNFs bind their physiological receptors