취급 제조사 2곳
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유전자 개요
CD49D (ITGA4) 유전자는 단백질의 인테그린 알파 사슬 계열 구성원을 암호화합니다. 인테그린은 세포 표면 부착 및 신호 전달 기능을 하는 알파 사슬과 베타 사슬로 구성된 이량체(heterodimeric) 막 단백질입니다. 이 유전자가 지정하는 전구단백질(preproprotein)은 단백질 분해 과정을 거쳐 알파 4 소단위를 구성하는 경쇄(light chain)와 중쇄(heavy chain)를 생성합니다. 이 소단위는 베타 1 또는 베타 7 소단위와 결합하여 세포 이동성에 관여할 수 있는 인테그린을 형성합니다. 이 인테그린은 다발성 경화증, 크론병 및 염증성 장 질환 치료를 위한 치료 표적입니다. 대체 스플라이싱(alternative splicing)으로 인해 여러 전사체 변이체가 생성됩니다.
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- 대표 논문 (PubMed) Maturation-dependent expression and function of the CD49d integrin on monocyte-derived human dendritic cells. · J Immunol (2000)CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression. · Blood (2020)The pathogenic relevance of the prognostic markers CD38 and CD49d in chronic lymphocytic leukemia. · Ann Hematol (2014)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Biosynth | F502-114362-01 | 61R-CD49DBT | CD49d antibody (PE) | Rat | Polyclonal | Murine; Cross: To be determined by end-user | FC, IHC, IP | 0.5 mg | |
| Biosynth | F502-114367-01 | 61R-CD49DCPE | CD49d antibody (PE) | Mouse | Polyclonal | Human; Cross: To be determined by end-user | FC | 100 piece | |
| Biosynth | F502-114368-01 | 61R-CD49DFT | CD49d antibody (PE) | Rat | Polyclonal | Murine; Cross: To be determined by end-user | FC, IHC | 0.5 mg | |
| Biosynth | F502-114372-01 | 61R-CD49FT2 | CD49d antibody (PE) | Mouse | Polyclonal | Human | FC, IP, WB | 100 piece | |
| Biosynth | F502-113404-01 | 61R-1258 | CD49d antibody (PE) | Rat | Polyclonal | Mouse | FC | 0.1 mg | |
| Biosynth | F502-113280-01 | 61R-1094 | CD49d antibody (FITC) | Rat | Polyclonal | Mouse | FC | 0.05 mg, 0.1 mg | |
| Biosynth | F502-113603-01 | 61R-1510 | CD49d antibody (biotin) | Rat | Polyclonal | Mouse | FC | 0.05 mg, 0.1 mg | |
| MyBioSource | R247-138629-01 | MBS2559061 | CD49d, Monoclonal Antibody | Mouse | Monoclonal | Human | FC/FACS | 20 Tests | |
| Biosynth | F502-107323-01 | 10R-CD49DH | CD49d antibody | Mouse | Monoclonal | Human; Cross: To be determined by end-user | FC, IP | 0.1 mg | |
| Biosynth | F502-107324-01 | 10R-CD49DM | CD49d antibody (Azide Free) | Rat | Monoclonal | Murine; Cross: To be determined by end-user | FC, IHC, IP | 0.5 mg | |
| Biosynth | F502-107322-01 | 10R-CD49DCMSP | CD49d antibody (Azide Free) | Rat | Monoclonal | Murine; Cross: To be determined by end-user | FC, IHC, IP | 0.5 mg | |
| Biosynth | F502-107321-01 | 10R-CD49DCMS | CD49d antibody (Azide Free) | Rat | Monoclonal | Murine; Cross: To be determined by end-user | FC, IHC, IP | 0.5 mg | |
| MyBioSource | R247-149941-01 | MBS4165644 | CD49d, Monoclonal Antibody | Rat | Monoclonal | Mouse | FC/FACS | ||
| Biosynth | F502-114364-01 | 61R-CD49DCHUPE | CD49d antibody (PE) | Mouse | Polyclonal | Human; Cross: To be determined by end-user | FC | 100 piece | |
| Biosynth | F502-114365-01 | 61R-CD49DCMSBT | CD49d antibody (PE) | Rat | Polyclonal | Murine; Cross: To be determined by end-user | FC, IHC, IP | 0.5 mg | |
| Biosynth | F502-114366-01 | 61R-CD49DCMSFT | CD49d antibody (PE) | Rat | Polyclonal | Murine; Cross: To be determined by end-user | FC, IHC | 0.5 mg | |
| Biosynth | F502-114363-01 | 61R-CD49DCHUFT2 | CD49d antibody (PE) | Mouse | Polyclonal | Human | FC, IP, WB | 100 piece | |
| Biosynth | F502-107320-01 | 10R-CD49DCHUP | CD49d antibody | Mouse | Monoclonal | Human; Cross: To be determined by end-user | FC, IP | 0.1 mg | |
| Biosynth | F502-100724-01 | 10-2973 | CD49d Antibody | Mouse | Monoclonal | Human, Dog | ICC/IF, Flow Cyt | 0.02 mg, 0.05 mg, 0.1 mg |