CD247 — 카탈로그 31건

Gene CD247 NCBI Gene 919

취급 제조사 5곳

Cusabio Abbexa Biosynth MyBioSource Cloud-Clone

국내 소싱 가능

31건

유전자 개요

이 유전자는 T세포 수용체(T-cell receptor) 제타 사슬 단백질을 암호화한다. 이 단백질은 T세포 수용체 알파/베타 및 감마/델타 이량체, 그리고 CD3-감마, -델타, -엡실론과 함께 T세포 수용체-CD3 복합체를 형성한다. 제타 사슬은 항원(antigen) 인식을 여러 세포 내 신호 전달 경로와 연결하는 데 중요한 역할을 한다. 항원 발현이 낮으면 면역 반응이 손상된다. 이 유전자에 대해 서로 다른 아이소폼을 암호화하는 두 개의 대체 스플라이싱 전사체 변이체가 발견되었다.

Co-inhibition by PD-1Downstream TCR signalingFCGR activationFCGR3A-mediated IL10 synthesisFCGR3A-mediated phagocytosisGeneration of second messenger moleculesImmunoregulatory interactions between a Lymphoid and a non-Lymphoid cellNef and signal transductionPhosphorylation of CD3 and TCR zeta chainsRegulation of actin dynamics for phagocytic cup formation

immunodeficiency 25cutaneous Leishmaniasiseosinophil countT-B- severe combined immunodeficiencyT-B+ severe combined immunodeficiencyT+ B+ severe combined immunodeficiencyasthmaneutrophil count

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) CD247 modulates blood pressure by altering T-lymphocyte infiltration in the kidney. · Hypertension (2014)Disrupting the phase separation of KAT8-IRF1 diminishes PD-L1 expression and promotes antitumor immunity. · Nat Cancer (2023)Recent Advances in Allogeneic CAR-T Cells. · Biomolecules (2020)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
Cusabio	T094-109833-01	CSB-RA244537A0HU	CD247 Recombinant Monoclonal Antibody	Rabbit	Monoclonal	Human	ELISA, FC	50μl, 100μl
Abbexa	F158-115705-01	abx329912	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody	Rabbit	Polyclonal	Human, Mouse, Rat, Monkey	ELISA, WB, IHC	50 µg
Abbexa	F158-114378-01	abx316120	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody (HRP)	Rabbit	Polyclonal	Human	ELISA	20 µg
Abbexa	F158-110785-01	abx231452	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA, WB, IHC, FCM, IP	100 µg
Abbexa	F158-100841-01	abx015796	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody	Mouse	Monoclonal	Human	ELISA, IHC, IF/ICC, FCM	100 µl
Abbexa	F158-100160-01	abx001675	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	WB, IF/ICC	60 µl
Abbexa	F158-113695-01	abx302589	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody	Rabbit	Polyclonal	Human	ELISA, WB, IHC, IF/ICC, IP	20 µg
Abbexa	F158-101424-01	abx027825	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody	Rabbit	Polyclonal	Human, Mouse	ELISA, WB, FCM	80 µl
Abbexa	F158-118030-01	abx402161	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody	Rabbit	Monoclonal	Human	ELISA, FCM	50 µl
Abbexa	F158-114380-01	abx316122	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody (Biotin)	Rabbit	Polyclonal	Human	ELISA	20 µg
Abbexa	F158-114924-01	abx323220	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody	Rabbit	Polyclonal	Human	ELISA, IHC	50 µg
Abbexa	F158-117597-01	abx377910	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody	Rabbit	Polyclonal	Human	ELISA, WB, IHC	50 µg
Abbexa	F158-101423-01	abx027824	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody	Rabbit	Polyclonal	Human	ELISA, WB, FCM	80 µl
Abbexa	F158-104773-01	abx111469	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA, WB, IHC	100 µl
Abbexa	F158-114379-01	abx316121	T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody (FITC)	Rabbit	Polyclonal	Human	FCM, IF	20 µg
Biosynth	F502-119110-01	70R-16262	CD247 antibody	Rabbit	Polyclonal	Human; Cross: Human, Mouse, Rat	ELISA, IHC, WB	50 ul
Biosynth	F502-103554-01	10R-2171	CD247 antibody	Mouse	Monoclonal	Human; Cross: Human	ELISA, FC, IF, WB	100 ul
MyBioSource	R247-190856-01	MBS8221871	CD247, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat, Rabbit, Monkey, Porcine	WB	0.03 mL
MyBioSource	R247-154497-01	MBS475989	CD247, Monoclonal Antibody	Mouse	Monoclonal	Human	WB; IHC; ICC; FC/FACS	0.1 mL

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
Abbexa	F158-121029-01	abx505781	Mouse T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) ELISA Kit	Mouse	ELISA	Tissue homogenates, cell lysates and other biological fluids.	< 31 pg/ml	96 tests
Cusabio	T094-102795-01	CSB-EL004904HU	Human T-cell surface glycoprotein CD3 zeta chain (CD247) ELISA kit	Homo sapiens (Human)	ELISA	serum, plasma, tissue homogenates, cell lysates	0.039 ng/mL	96T,5×96T,10×96T
MyBioSource	R247-122224-01	MBS166681	T-cell surface glycoprotein CD3 zeta chain (CD247), ELISA Kit	Human	ELISA	Serum, plasma, cell culture supernates, Ascites, tissue homogenates or other biological fluids	0.026ng/ml	48-Strip-Wells
MyBioSource	R247-202871-01	MBS926331	CD247 molecule, ELISA Kit	Human	ELISA	Serum, plasma, tissue homogenates, Cell lysates	The minimum detectable dose of human CD247 is typically less than 0.039 ng/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.	24-Strip-Wells
Abbexa	F158-121030-01	abx505782	Pig T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) ELISA Kit	Pig	ELISA	Tissue homogenates, cell lysates and other biological fluids.		96 tests
Abbexa	F158-117841-01	abx386388	Human T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) ELISA Kit	Human	ELISA	Tissue homogenates, cell lysates and other biological fluids.		96 tests

제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
Abbexa	F158-123151-01	abx652139	Human T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Protein	E. coli	Human	WB, SDS-PAGE	10 µg
Abbexa	F158-123001-01	abx651259	Human T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Peptide (OVA)	Synthetic	Human	WB, SDS-PAGE	100 µg
Abbexa	F158-123152-01	abx652140	Mouse T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Protein	E. coli	Mouse	WB, SDS-PAGE	10 µg
Abbexa	F158-124316-01	abx680140	Human T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Protein	Insect	Human	SDS-PAGE	1 µg
Cloud-Clone	T813-132406-01	RPA865Hu01	Recombinant Cluster Of Differentiation 247 (CD247)	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-132407-01	RPA865Mu01	Recombinant Cluster Of Differentiation 247 (CD247)	E.coli	Murine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg

CD247 — 카탈로그 31건

유전자 개요

관련 표적