CAMK2A — 카탈로그 24건

Gene CAMK2A NCBI Gene 815

취급 제조사 4곳

MyBioSource Biosynth Cloud-Clone ELK Biotechnology

국내 소싱 가능

24건

유전자 개요

이 유전자는 세린/트레오닌 단백질 키나아제(serine/threonine protein kinases) 계열 및 칼슘/칼모듈린 의존성 단백질 키나아제(Ca(2+)/calmodulin-dependent protein kinases) 서브패밀리(subfamily)에 속하는 단백질을 생성한다. 칼슘 신호 전달은 글루탐산염 시냅스(glutamatergic synapses)에서의 가소성 여러 측면에 중요하다. 이 칼슘 칼모듈린 의존성 단백질 키나아제는 알파, 베타, 감마, 델타의 네 가지 다른 사슬로 구성된다. 이 유전자에 의해 지정되는 알파 사슬은 해마 장기 강화(hippocampal long-term potentiation, LTP) 및 공간 학습에 필요하다. 이 단백질은 칼슘-칼모듈린(CaM) 의존성 활성 외에도 자가 인산화(autophosphorylation)를 거쳐 CaM 비의존성 활성을 나타낼 수 있다. 이 유전자에 대해 서로 다른 아이소폼(isoforms)를 지정하는 여러 전사 변이체(transcript variants)가 확인되었다.

Assembly and cell surface presentation of NMDA receptorsCa2+ pathwayCaMK IV-mediated phosphorylation of CREBHSF1-dependent transactivationInterferon gamma signalingIon homeostasisIon transport by P-type ATPasesLong-term potentiationNegative regulation of NMDA receptor-mediated neuronal transmissionParadoxical activation of RAF signaling by kinase inactive BRAF

intellectual disability, autosomal dominant 53Intellectual disabilityautosomal recessive non-syndromic intellectual disabilitysmoking initiationgut microbiome measurementautosomal dominant non-syndromic intellectual disabilitycomplex neurodevelopmental disordersitting height measurement

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. · Cell Rep (2018)De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability. · Am J Hum Genet (2017)Rare variants in neuronal excitability genes influence risk for bipolar disorder. · Proc Natl Acad Sci U S A (2015)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
MyBioSource	R247-213884-01	MBS9608431	CAMK2A, Polyclonal Antibody	Rabbit	Polyclonal	Human	WB; ELISA	0.1 mL
Biosynth	F502-118973-01	70R-16137	CAMK2A antibody	Rabbit	Polyclonal	Human; Cross: Human, Mouse, Rat	ELISA, WB	50 ul
Cloud-Clone	T813-124939-01	PAD331Ra01	Polyclonal Antibody to Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)	Rabbit	Polyclonal	Rat	WB; IHC	100µl
Cloud-Clone	T813-114461-01	MAD331Ra21	Monoclonal Antibody to Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)	Mouse	Monoclonal	Rat	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-124938-01	PAD331Mu01	Polyclonal Antibody to Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)	Rabbit	Polyclonal	Murine	WB; IHC	100µl
Cloud-Clone	T813-114460-01	MAD331Hu21	Monoclonal Antibody to Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)	Mouse	Monoclonal	Human	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-124937-01	PAD331Hu01	Polyclonal Antibody to Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)	Rabbit	Polyclonal	Human	WB; IHC; ICC; IP.	100µl
MyBioSource	R247-188744-01	MBS800909	CaMKII (Camk2a), Monoclonal Antibody	Mouse	Monoclonal	Human, Rat	ELISA; IF; IP; WB	0.1 mg
MyBioSource	R247-188810-01	MBS802257	CaMKII (alpha-specific) (Camk2a), Monoclonal Antibody	Mouse	Monoclonal	Human, Mouse, Rat, Bovine	IF; IP; WB; IHC; RIA; ELISA	0.1 mg
MyBioSource	R247-200940-01	MBS9201596	CAMK2A, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	WB; ELISA; IHC	0.08 mL
MyBioSource	R247-188901-01	MBS804309	CaMKII (alpha-specific) (Camk2a), Monoclonal Antibody	Mouse	Monoclonal	Human, Mouse, Rat, Bovine	IF; IP; WB; IHC; RIA; ELISA	0.1 mg
MyBioSource	R247-188760-01	MBS801278	CaMKII (Camk2a), Monoclonal Antibody	Mouse	Monoclonal	Human, Rat	ELISA; IF; IP; WB	0.1 mg
Biosynth	F502-136391-01	70R-51815	CAMK2A antibody	Rabbit	Polyclonal	Recognizes endogenous levels of CaMK2 alpha/delta protein; Cross: Mouse, Rat, Bovine, Chicken, Pig, Sheep	WB, IHC, IF, ICC	100 ul
Biosynth	F502-117721-01	70R-14946	CAMK2 A/B antibody (Thr286)	Rabbit	Polyclonal	Human, Mouse, Rabbit, Rat; Cross: Expected: Zebrafish	WB	100 ul
ELK Biotechnology	T376-116740-01	ES1415	CaMKIIα/β/δ (phospho Thr305) rabbit pAb	Rabbit	Polyclonal	Human;Mouse;Rat	WB;IHC;IF;ELISA	50μL
MyBioSource	R247-196591-01	MBS858961	CaMK2alpha/delta, Antibody			Human, Mouse, Rat	WB; IHC; IF; ELISA	0.1 mg

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
Cloud-Clone	T813-147249-01	SED331Hu	ELISA Kit for Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)	Human	ELISA	Tissue homogenates and other biological fluids.	0.064ng/mL.	96T
Cloud-Clone	T813-147251-01	SED331Ra	ELISA Kit for Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)	Rat	ELISA	tissue homogenates, cell lysates and other biological fluids	0.057ng/mL.	96T
Cloud-Clone	T813-147250-01	SED331Mu	ELISA Kit for Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)	Murine	ELISA	tissue homogenates, cell lysates and other biological fluids	0.117ng/mL.	96T
MyBioSource	R247-179962-01	MBS7209254	Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMK2A), ELISA Kit	Goat	ELISA	Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate		48-Strip-Wells

제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
Cloud-Clone	T813-137384-01	RPD331Hu01	Recombinant Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-137386-01	RPD331Ra01	Recombinant Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)	E.coli	Rat	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-137385-01	RPD331Mu01	Recombinant Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2a)	E.coli	Murine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
MyBioSource	R247-215484-01	MBS964219	Calcium/calmodulin-dependent protein kinase type II subunit alpha (Camk2a), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell			0.02 mg

CAMK2A — 카탈로그 24건

유전자 개요

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