CACNB2 — 카탈로그 17건
Gene CACNB2
NCBI Gene 783
취급 제조사 3곳
국내 소싱 가능
17건
유전자 개요
CACNB2 유전자는 전압 개폐 칼슘 채널 단백질의 소단위를 암호화한다. 이 단백질은 전압 개폐 칼슘 채널 슈퍼패밀리(superfamily)에 속한다. 이 유전자의 산물은 자가면역 질환인 람베르트-이튼 근무력 증후군(Lambert-Eaton myasthenic syndrome)에서 항원 표적으로 처음 확인되었다. 이 유전자의 돌연변이는 브루가다 증후군(Brugada syndrome)과 관련이 있다. 서로 다른 아이소폼(isoform)을 암호화하는 대체 스플라이싱 변이체들이 기술되었다. [RefSeq 제공, 2013년 2월]
Adrenaline,noradrenaline inhibits insulin secretionMechanical load activates signaling by PIEZO1 and integrins in osteocytesNCAM1 interactionsPhase 0 - rapid depolarisationPhase 2 - plateau phasePresynaptic depolarization and calcium channel openingRegulation of insulin secretionSensory processing of sound by inner hair cells of the cochlea
cardiovascular diseaseBrugada syndromesystolic blood pressurehypertensiondiastolic blood pressuremean arterial pressurebody mass indexaspartate aminotransferase measurement
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. · Lancet (2013)Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies. · Eur J Transl Myol (2022)Genetic variations in CYP17A1, CACNB2 and PLEKHA7 are associated with blood pressure and/or hypertension in She ethnic minority of China. · Atherosclerosis (2011)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-108187-01 | CSB-PA804482LA01HU | CACNB2 Antibody | Rabbit | Polyclonal | Human | ELISA, IHC, IF | 50μg, 100μg | |
| Biosynth | F502-117786-01 | 70R-1501 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit | WB | 100 ul | |
| Biosynth | F502-135102-01 | 70R-5064 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit | WB | 100 ul | |
| Biosynth | F502-135124-01 | 70R-5066 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Human | WB | 100 ul | |
| Biosynth | F502-135442-01 | 70R-5095 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Rabbit | WB | 100 ul | |
| Biosynth | F502-135453-01 | 70R-5096 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit | WB | 100 ul | |
| Biosynth | F502-134930-01 | 70R-5048 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish | WB | 100 ul | |
| Biosynth | F502-135091-01 | 70R-5063 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish | WB | 100 ul | |
| Biosynth | F502-117861-01 | 70R-1508 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish | WB | 100 ul | |
| Biosynth | F502-117870-01 | 70R-1509 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit | WB | 100 ul | |
| Biosynth | F502-135233-01 | 70R-5076 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Human | WB | 100 ul | |
| Biosynth | F502-135409-01 | 70R-5092 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit | WB | 100 ul | |
| MyBioSource | R247-188737-01 | MBS800762 | Cavbeta2 (Cacnb2), Monoclonal Antibody | Mouse | Monoclonal | Human, Mouse, Rat | WB; IP; IHC | 0.1 mg | |
| MyBioSource | R247-200384-01 | MBS9140681 | CACNB2, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC | ||
| MyBioSource | R247-188928-01 | MBS804861 | Cavbeta2 (Cacnb2), Monoclonal Antibody | Mouse | Monoclonal | Human, Mouse, Rat | WB; IP; IHC; ICC; IF; AM | 0.1 mg | |
| MyBioSource | R247-188836-01 | MBS802782 | Cavbeta2 (Cacnb2), Monoclonal Antibody | Mouse | Monoclonal | WB; IP; IHC | 0.1 mg | ||
| Biosynth | F502-138929-01 | 70R-8062 | CACNB2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit | WB | 100 ul |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
CACNA1C
Phase 2 - plateau phase
CACNA1H
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
AKT1
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
ITGB1
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
ITGB3
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
PANX1
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
P2RX7
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
ITGA5
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes