BUB3 — 카탈로그 44건
Gene BUB3
NCBI Gene 9184
취급 제조사 3곳
국내 소싱 가능
44건
유전자 개요
BUB3가 암호화하는 단백질은 스핀들 체크포인트(spindle checkpoint) 기능에 관여한다. 이 단백질은 4개의 WD 반복 도메인(WD repeat domain)을 포함하며 효모 BUB3 단백질과 서열 유사성을 갖는다. 서로 다른 아이소폼(isoform)을 지정하는 대안 전사 스플라이스 변이체(alternative transcriptional splice variant)들이 특성화되었다.
APC-Cdc20 mediated degradation of Nek2AAPC/C:Cdc20 mediated degradation of mitotic proteinsAmplification of signal from unattached kinetochores via a MAD2 inhibitory signalCdc20:Phospho-APC/C mediated degradation of Cyclin AEML4 and NUDC in mitotic spindle formationInactivation of APC/C via direct inhibition of the APC/C complexMitotic PrometaphaseRHO GTPases Activate ForminsResolution of Sister Chromatid CohesionSeparation of Sister Chromatids
smoking initiationbody mass indexmosaic variegated aneuploidy syndromeheel bone mineral densitybody heightobesityurea measurementblood urea nitrogen amount
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase. · J Cell Biol (1998)Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma. · J Clin Oncol (2017)Kinetochore-microtubule interactions "in check" by Bub1, Bub3 and BubR1: The dual task of attaching and signalling. · Cell Cycle (2008)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| MyBioSource | R247-173778-01 | MBS7047773 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | ELISA; WB; IHC | 0.05 mg | |
| MyBioSource | R247-209883-01 | MBS9436686 | Bub3, Monoclonal Antibody | Rabbit | Monoclonal | Human, Mouse, Rat | WB; ICC; IF; IP; IHC; FC/FACS | 0.05 mL | |
| MyBioSource | R247-173780-01 | MBS7047775 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA | 0.05 mg | |
| MyBioSource | R247-210441-01 | MBS9457527 | Bub3, Monoclonal Antibody | Rabbit | Monoclonal | Human, Mouse, Rat | Most Applications | 0.1 mL | |
| MyBioSource | R247-173781-01 | MBS7047776 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA | 0.05 mg | |
| MyBioSource | R247-154561-01 | MBS4762280 | BUB3, Monoclonal Antibody | Rabbit | Monoclonal | Human, Mouse, Rat | WB; IHC-P; ICC; IF; IP; FC/FACS | 0.1 mL | |
| MyBioSource | R247-173779-01 | MBS7047774 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA | 0.05 mg | |
| Biosynth | F502-135154-01 | 70R-50687 | BUB3 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of BUB3 protein; Cross: Monkey | WB, IHC, IF, ICC, IP | 100 ul | |
| Biosynth | F502-118874-01 | 70R-16047 | BUB3 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IF, WB | 50 ul | |
| Biosynth | F502-127864-01 | 70R-32297 | BUB3 antibody | Rabbit | Polyclonal | BUB3 antibody detects endogenous levels of total BUB3 protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-117502-01 | 70R-14182 | BUB3 antibody | Rabbit | Polyclonal | Human | WB, IHC-P | 0.1 mg | |
| MyBioSource | R247-177569-01 | MBS7144593 | bub-3, Polyclonal Antibody | Rabbit | Polyclonal | Caenorhabditis elegans | ELISA; WB (Western Blot) | ||
| MyBioSource | R247-137572-01 | MBS2535225 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; IHC; IF | 0.06 mL | |
| MyBioSource | R247-177277-01 | MBS7138312 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Schizosaccharomyces pombe (strain 972, 24843)(Fission yeast) | ELISA; WB (Western Blot) | ||
| MyBioSource | R247-123104-01 | MBS175512 | Bub3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; Immunohistochemistry (IHC) Paraffin; Immunohistochemistry (IHC) Formalin; Immunocytochemistry ICC | 0.01 mg | |
| MyBioSource | R247-115820-01 | MBS140479 | BUB3, Monoclonal Antibody | Mouse | Monoclonal | Human | ELISA; WB | 0.005 mg | |
| MyBioSource | R247-193440-01 | MBS8422862 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | IF | 0.12 mL | |
| MyBioSource | R247-208425-01 | MBS9413069 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB | 0.1 mL | |
| MyBioSource | R247-196279-01 | MBS8572967 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IF | 0.1 mL | |
| MyBioSource | R247-210773-01 | MBS9470738 | Bub3, Recombinant Antibody | Rabbit | Monoclonal | Human, Mouse, Rat | WB; IHC; ICC; IF; IP; FC/FACS | 0.05 mL | |
| MyBioSource | R247-137040-01 | MBS2524278 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | ELISA; WB | 0.02 mL | |
| MyBioSource | R247-195258-01 | MBS8546170 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IF | 0.1 mL | |
| MyBioSource | R247-123117-01 | MBS1755191 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Rat | WB; FC/FACS; ELISA | 0.01 mg | |
| MyBioSource | R247-207695-01 | MBS9400687 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; IF | 0.05 mL | |
| MyBioSource | R247-198473-01 | MBS9125379 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF | 0.02 mL | |
| MyBioSource | R247-124937-01 | MBS200314 | BUB3, Monoclonal Antibody | Mouse | Monoclonal | Human | ELISA; WB | 0.05 mL | |
| MyBioSource | R247-177955-01 | MBS7153917 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Saccharomyces cerevisiae (strain 204508, S288c)(Baker's yeast) | ELISA; WB (Western Blot) | ||
| MyBioSource | R247-193439-01 | MBS8422861 | BUB3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; ELISA | ||
| MyBioSource | R247-195947-01 | MBS8565898 | BUB3, Monoclonal Antibody | Rabbit | Monoclonal | Human, Mouse, Rat | 0.1 mL | ||
| Biosynth | F502-136840-01 | 70R-5623 | BUB3 antibody | Rabbit | Polyclonal | Human,Mouse,Rat | WB | 100 ul | |
| Biosynth | F502-102759-01 | 10R-11290 | BUB3 antibody | Mouse | Monoclonal | Human | ELISA, WB | 100 ul | |
| MyBioSource | R247-196575-01 | MBS858793 | bub3, Antibody | Rabbit | Human, Mouse, Rat | WB; IHC | 0.1 mL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
BUB1B
Inactivation of APC/C via direct inhibition of the APC/C complex
UBE2C
Inactivation of APC/C via direct inhibition of the APC/C complex
CDC23
Inactivation of APC/C via direct inhibition of the APC/C complex
UBE2D1
Inactivation of APC/C via direct inhibition of the APC/C complex
UBE2S
Inactivation of APC/C via direct inhibition of the APC/C complex
UBB
APC-Cdc20 mediated degradation of Nek2A
PSMA1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
PSMA3
Cdc20:Phospho-APC/C mediated degradation of Cyclin A