해외 연구시약 수입·전문 취급 · 국내 대리점 관련 문의

BBC3 — 카탈로그 15건

Gene BBC3 NCBI Gene 27113
취급 제조사 4곳
AbbexaMyBioSourceBiosynthELK Biotechnology
국내 소싱 가능
15건

유전자 개요

BBC3 유전자는 BCL-2 단백질 패밀리 구성원을 암호화하며, 이는 BH3-only pro-apoptotic(세포자멸사 촉진) 서브패밀리(subfamily)에 속한다. 이 단백질은 직접 활성화 단백질과 협력하여 미토콘드리아 외막(membrane) 투과성을 유도하고 세포자멸사(apoptosis)를 일으키며, 항세포자멸사(anti-apoptotic) Bcl-2 패밀리 구성원에 결합해 미토콘드리아 기능 장애와 카스파제(caspase) 활성화를 초래할 수 있다. 따라서 이 유전자는 암(cancer) 치료와 조직 손상 관련 잠재적 약물 표적으로 주목받는다.

Activation of PUMA and translocation to mitochondriaBH3-only proteins associate with and inactivate anti-apoptotic BCL-2 membersFOXO-mediated transcription of cell death genesTP53 Regulates Transcription of Genes Involved in Cytochrome C Release
neurodegenerative diseaselean body massbody composition measurementAbnormality of the skeletal systemmonocyte countIGF-1 measurementbody heightserum gamma-glutamyl transferase measurement
데이터 출처 · 근거

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

견적제조사Cat NoMfr No제품명HostClonalityReactivityApplicationSize
AbbexaF158-119675-01abx432397Bcl2-Binding Component 3 (BBC3) AntibodyGoatPolyclonalHumanP-ELISA, WB200 µl
AbbexaF158-101189-01abx025028Bcl-2-Binding Component 3 (BBC3) AntibodyRabbitPolyclonalHumanELISA, WB, IHC80 µl
AbbexaF158-116829-01abx348761Bcl-2-binding component 3, isoforms 1/2 (BBC3) Antibody (FITC)RabbitPolyclonalHumanFCM, IF50 µl
AbbexaF158-116827-01abx348759Bcl-2-binding component 3, isoforms 1/2 (BBC3) AntibodyRabbitPolyclonalHuman, RatELISA, WB20 µl
AbbexaF158-116830-01abx348762Bcl-2-binding component 3, isoforms 1/2 (BBC3) Antibody (Biotin)RabbitPolyclonalHumanELISA50 µl
AbbexaF158-116278-01abx339653Bcl-2-Binding Component 3 (BBC3) AntibodyRabbitPolyclonalHumanELISA, WB50 µl
AbbexaF158-116828-01abx348760Bcl-2-binding component 3, isoforms 1/2 (BBC3) Antibody (HRP)RabbitPolyclonalHumanELISA50 µl
AbbexaF158-115396-01abx327163Bcl-2-Binding Component 3 (BBC3) AntibodyRabbitPolyclonalHuman, Mouse, RatELISA, WB50 µg
MyBioSourceR247-119512-01MBS151208PUMA (BBC3), Polyclonal AntibodyRabbitPolyclonalHuman, MouseELISA; WB; ICC; IF0.1 mg
MyBioSourceR247-136865-01MBS2520788BBC3, Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, RatELISA; WB0.02 mL
AbbexaF158-120226-01abx456991Bcl-2-Binding Component 3, Isoforms 1/2 (BBC3) AntibodyRabbitHumanELISA, WB, IHC50 µg
BiosynthF502-140433-0170R-9636BBC3 antibodyRabbitPolyclonalHuman; Cross: HumanWB100 ul
ELK BiotechnologyT376-119379-01ES3285PUMA rabbit pAbRabbitPolyclonalHuman;Mouse;RatWB IF;ELISA50μL

관련 표적

같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.

BCL2L11 BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members TP53 Activation of PUMA and translocation to mitochondria TP73 Activation of PUMA and translocation to mitochondria BID BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members TP63 Activation of PUMA and translocation to mitochondria CREBBP FOXO-mediated transcription of cell death genes STAT3 BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members BCL2 BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
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