ATF2 — 카탈로그 67건
Gene ATF2
NCBI Gene 1386
국내 소싱 가능
67건
유전자 개요
ATF2는 DNA 결합 단백질의 류신 지퍼(leucine zipper) 계열에 속하는 전사인자(transcription factor)를 암호화하며, 기전적으로 구별되는 기능을 함께 수행하는 능력에 근거해 문라이팅 단백질(moonlighting protein)로 확인된 단백질이다. 이 단백질은 cAMP 반응 요소(CRE)에 결합하여 동종이량체 또는 c-Jun과의 이종이량체를 형성하고 CRE 의존적 전사를 촉진하며, 시험관 내에서 히스톤 H2B와 H4를 특이적으로 아세틸화하는 히스톤 아세틸트랜스퍼라아제(HAT)로서 염색질(chromatin) 구성 요소에 직접 작용해 전사를 활성화할 수 있다. 또한 전사 조절에서의 역할과는 독립적으로 세포의 DNA 손상 반응에도 관여할 수 있다.
Activation of the AP-1 family of transcription factorsEstrogen-dependent gene expressionExpression of BMAL (ARNTL), CLOCK, and NPAS2HATs acetylate histonesHeme signalingNGF-stimulated transcriptionRegulation of PTEN gene transcriptionResponse of EIF2AK4 (GCN2) to amino acid deficiencyTP53 Regulates Transcription of DNA Repair GenesTranscriptional activation of mitochondrial biogenesis
Abnormality of the skeletal systemPancreatic pseudocystdiaphragm diseaseneurodegenerative diseaselymphocyte countbody fat percentagebody heightglomerular filtration rate
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) ATF2, a paradigm of the multifaceted regulation of transcription factors in biology and disease. · Pharmacol Res (2017)The role of ATF-2 in oncogenesis. · Bioessays (2008)ATF2: a transcription factor that elicits oncogenic or tumor suppressor activities. · Cell Cycle (2008)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-109338-01 | CSB-RA002270A71phHU | Phospho-ATF2 (T71) Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human | ELISA, WB, IF | 50μl, 100μl | |
| Cusabio | T094-109337-01 | CSB-RA002270A0HU | ATF2 Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human | ELISA, WB, IHC | 50μl, 100μl | |
| MyBioSource | R247-212255-01 | MBS9600947 | ATF2, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; IP; ELISA | 0.1 mL | |
| MyBioSource | R247-212444-01 | MBS9601783 | ATF2, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; IP; ELISA | 0.1 mL | |
| MyBioSource | R247-212443-01 | MBS9601782 | ATF2, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; IP; ELISA | 0.1 mL | |
| Biosynth | F502-132010-01 | 70R-37112 | ATF2 antibody (Thr69or51) | Rabbit | Polyclonal | ATF2 antibody (Thr69or51) detects endogenous levels of ATF2 only when phosphorylated at threonine 69 or 51; Cross: Mouse, Rat | IHC, IF | 0.1 mg | |
| Biosynth | F502-118692-01 | 70R-15880 | ATF2 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| Biosynth | F502-131481-01 | 70R-36464 | ATF2 antibody (Thr73or55) | Rabbit | Polyclonal | ATF2 antibody (Thr73or55) detects endogenous levels of ATF2 only when phosphorylated at threonine 73 or 55; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-131474-01 | 70R-36456 | ATF2 antibody | Rabbit | Polyclonal | ATF2 antibody detects endogenous levels of ATF2 protein around Threonine 71 or 53; Cross: Mouse, Rat | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-129797-01 | 70R-34463 | ATF2 antibody (Ser472) | Rabbit | Polyclonal | ATF2 antibody detects endogenous levels of ATF2 only when phosphorylated at serine 472; Cross: Mouse, Rat | IHC, ELISA | 0.1 mg | |
| Biosynth | F502-131028-01 | 70R-35902 | ATF2 antibody (Thr71or53) | Rabbit | Polyclonal | ATF2 antibody (Thr71or53) detects endogenous levels of ATF2 only when phosphorylated at Threonine 71 or 53; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-131079-01 | 70R-35958 | ATF2 antibody (Ser62or44) | Rabbit | Polyclonal | ATF2 antibody (Ser62or44) detects endogenous levels of ATF2 only when phosphorylated at serine 62 or 44; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-128675-01 | 70R-33436 | ATF2 antibody (Ser480) | Rabbit | Polyclonal | ATF2 antibody detects endogenous levels of ATF2 only when phosphorylated at serine 480; Cross: Mouse, Rat | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-102744-01 | 10R-11248 | ATF2 antibody | Mouse | Monoclonal | Human; Cross: Mouse | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-130298-01 | 70R-35022 | ATF2 antibody | Rabbit | Polyclonal | ATF2 antibody detects endogenous levels of total ATF2 proteinATF2 antibody detects endogenous levels of total ATF2 protein; Cross: Mouse, Rat | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-131575-01 | 70R-36584 | ATF2 antibody | Rabbit | Polyclonal | ATF2 antibody detects endogenous levels of total ATF2 protein; Cross: Mouse, Rat | WB, IHC IF, ELISA | 0.1 mg | |
| Biosynth | F502-132394-01 | 70R-37469 | ATF2 antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | WB, IHC, IF | 0.1 mg | |
| Biosynth | F502-132397-01 | 70R-37471 | ATF2 antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | WB, IHC, IF | 0.1 mg | |
| Biosynth | F502-129798-01 | 70R-34464 | ATF2 antibody | Rabbit | Polyclonal | ATF2 antibody detects endogenous levels of total ATF2 protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-132009-01 | 70R-37111 | ATF2 antibody (Ser62or44) | Rabbit | Polyclonal | ATF2 antibody (Ser62or44) detects endogenous levels of ATF2 only when phosphorylated at serine 62 or 44; Cross: Mouse, Rat | IHC | 0.1 mg | |
| Biosynth | F502-131936-01 | 70R-37027 | ATF2 antibody (Ser112or94) | Rabbit | Polyclonal | ATF2 antibody (Ser112or94) detects endogenous levels of ATF2 only when phosphorylated at serine 112 or 94; Cross: Mouse, Rat | WB, IHC ELISA | 0.1 mg | |
| Biosynth | F502-130343-01 | 70R-35079 | ATF2 antibody (Thr69or51) | Rabbit | Polyclonal | ATF2 Antibody detects endogenous levels of ATF2 only when phosphorylated at Threonine 69 or 51; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-128676-01 | 70R-33437 | ATF2 antibody | Rabbit | Polyclonal | ATF2 antibody detects endogenous levels of total ATF2 protein; Cross: Rat | IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-132012-01 | 70R-37114 | ATF2 antibody (Thr73or55) | Rabbit | Polyclonal | ATF2 antibody (Thr73or55) detects endogenous levels of ATF2 only when phosphorylated at threonine 73 or 55; Cross: Mouse, Rat | IHC, IF | 0.1 mg | |
| Biosynth | F502-132398-01 | 70R-37472 | ATF2 antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-102907-01 | 10R-1203 | ATF2 antibody | Mouse | Monoclonal | Human; Cross: Human. Other species not studied | Dot Blot, IP | 0.05 mg | |
| Biosynth | F502-130650-01 | 70R-35456 | ATF2 antibody | Rabbit | Polyclonal | ATF2 antibody detects endogenous levels of total ATF2 protein; Cross: Mouse, Rat | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-132396-01 | 70R-37470 | ATF2 antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-131619-01 | 70R-36636 | ATF2 antibody | Rabbit | Polyclonal | ATF2 antibody detects endogenous levels of ATF2 protein around Threonine 51 or 53; Cross: Mouse, Rat | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-132399-01 | 70R-37473 | ATF2 antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-133954-01 | 70R-49590 | ATF2 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of ATF2 protein; Cross: Mouse, Monkey | WB | 100 ul | |
| Biosynth | F502-132013-01 | 70R-37115 | ATF2 antibody (Ser112or94) | Rabbit | Polyclonal | ATF2 antibody (Ser112or94) detects endogenous levels of ATF2 only when phosphorylated at serine 112 or 94; Cross: Mouse, Rat | IHC | 0.1 mg | |
| Biosynth | F502-133955-01 | 70R-49591 | ATF2 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of ATF2 protein; Cross: Mouse, Rat, Chicken | WB, IHC, IP | 100 ul | |
| Biosynth | F502-132011-01 | 70R-37113 | ATF2 antibody (Thr71or53) | Rabbit | Polyclonal | ATF2 antibody (Thr71or53) detects endogenous levels of ATF2 only when phosphorylated at threonine 71 or 53; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| MyBioSource | R247-123591-01 | MBS177474 | Cyclic AMP-dependent transcription factor ATF-2 (ATF2), Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC-P; IHC-F | 0.01 mg | |
| MyBioSource | R247-124278-01 | MBS191042 | ATF2, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Dog | IB; Immunohistochemistry (IHC) Paraffin; IF | 0.1 mL | |
| Biosynth | F502-109026-01 | 20R-2213 | ATF2 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IF, IHC, WB | 0.05 mg | ||
| Biosynth | F502-109028-01 | 20R-2215 | ATF2 antibody | Rabbit | Human; Cross: Human | IF, IHC, WB | 0.05 mg | ||
| Biosynth | F502-108718-01 | 20R-1900 | ATF2 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| Biosynth | F502-109030-01 | 20R-2217 | ATF2 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| Biosynth | F502-108717-01 | 20R-1899 | ATF2 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IF, IHC, WB | 0.05 mg | ||
| Biosynth | F502-109029-01 | 20R-2216 | ATF2 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| Biosynth | F502-108714-01 | 20R-1896 | ATF2 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| Biosynth | F502-109027-01 | 20R-2214 | ATF2 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| Biosynth | F502-108716-01 | 20R-1898 | ATF2 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| Biosynth | F502-108715-01 | 20R-1897 | ATF2 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IF, IHC, WB | 0.05 mg | ||
| Biosynth | F502-108051-01 | 20-AS62 | ATF2 antibody | Sheep | To be determined by end-user | User optimized | 0.2 mg | ||
| MyBioSource | R247-112876-01 | MBS125882 | ATF2-T53, Antibody | Rabbit | Human, Mouse, Rat | WB; IHC; IF | 0.02 mL | ||
| MyBioSource | R247-134901-01 | MBS241136 | ATF2, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | Immunohistochemistry (IHC - Paraffin); WB | ||
| Biosynth | F502-136048-01 | 70R-51501 | ATF2 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of ATF2 protein; Cross: Mouse, Rat, Bovine, Cat | WB, IHC, IP | 100 ul | |
| Biosynth | F502-136045-01 | 70R-51499 | ATF2 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of ATF2 protein; Cross: Mouse, Rat, Bovine, Cat | WB, IHC, IP | 100 ul | |
| Biosynth | F502-136047-01 | 70R-51500 | ATF2 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of ATF2 protein; Cross: Mouse, Rat, Chicken | WB, IHC, IP | 100 ul | |
| Biosynth | F502-136044-01 | 70R-51498 | ATF2 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of ATF2 protein; Cross: Mouse, Rat, Chicken | WB, IHC, IP | 100 ul | |
| ELK Biotechnology | T376-120244-01 | ES4802 | ATF-2 (phospho Ser480) rabbit pAb | Rabbit | Polyclonal | Human;Rat | WB;IHC;IF;ELISA | 50μL | |
| ELK Biotechnology | T376-120245-01 | ES4806 | ATF-2 rabbit pAb | Rabbit | Polyclonal | Human;Rat | IHC;IF;ELISA | 50μL | |
| Biosynth | F502-117719-01 | 70R-14943 | ATF2 antibody | Rabbit | Polyclonal | WB, IHC | 100 ul |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
FOS
Activation of the AP-1 family of transcription factors
JUN
Activation of the AP-1 family of transcription factors
MAPK1
Activation of the AP-1 family of transcription factors
MAPK3
Activation of the AP-1 family of transcription factors
MAPK14
Activation of the AP-1 family of transcription factors
MAPK11
Activation of the AP-1 family of transcription factors
MAPK8
Activation of the AP-1 family of transcription factors
MAPK9
Activation of the AP-1 family of transcription factors