POMC (ACTH) — 카탈로그 50건

POMC

Gene ACTH NCBI Gene 5443

취급 제조사 5곳

Enzo Life Sciences Cloud-Clone Biosynth MyBioSource Cusabio

국내 소싱 가능

50건

유전자 개요

ACTH는 프로호르몬 전환효소(prohormone convertase)라 불리는 서브틸리신 유사 효소에 의해 광범위하고 조직 특이적인 번역 후 절단 가공을 거치는 전구단백질에서 유래하며, 이 전구단백질의 8개 잠재적 절단 부위는 조직 유형과 이용 가능한 전환효소에 따라 최대 10종의 생물학적 활성 펩타이드(peptide)를 만들어낸다. 이 단백질은 주로 뇌하수체 전엽의 부신피질자극세포(corticotroph)에서 4개 절단 부위가 사용되어 합성되며, 정상적인 스테로이드 생성과 부신 무게 유지에 필수적인 ACTH와 베타-지질자극호르몬(lipotropin beta)이 주요 최종 산물이고, 시상하부·태반·상피 등 다른 조직에서는 모든 절단 부위가 쓰여 통증과 에너지 항상성, 멜라닌세포 자극, 면역 조절에 관여하는 멜라노트로핀·지질자극호르몬·엔도르핀이 생성된다. 이 유전자의 돌연변이는 조기 발병 비만, 부신 기능 부전, 붉은 머리카락 색소침착과 연관되어 있다.

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
대표 논문 (PubMed) NIH conference. Clinical applications of corticotropin-releasing factor. · Ann Intern Med (1985)Adenylate cyclase of GH and ACTH producing tumors of human: activation by non-specific hormones and other bioactive substances. · J Clin Endocrinol Metab (1977)VIP stimulates ACTH release and adenylate cyclase in human ACTH-secreting pituitary adenomas. · Eur J Pharmacol (1982)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
Enzo Life Sciences	R365-103222-01	ENZ-ABS851-1000	ACTH monoclonal antibody (AH26)	Mouse	Monoclonal	Does not cross-react with CLIP (aa 17-39 of ACTH).	IHC (PS)	1 ml
Cloud-Clone	T813-108792-01	LAA836Hu81	FITC-Linked Polyclonal Antibody to Adrenocorticotropic Hormone (ACTH)	Rabbit	Antibody labeling	Human	WB; IHC; ICC; IF.	100µl
Biosynth	F502-100606-01	10-2850	ACTH antibody	Mouse	Monoclonal	Human	ELISA, RIA, Lateral Flow	1 mg
Biosynth	F502-101408-01	10-A32A	ACTH antibody	Mouse	Monoclonal	Human; Cross: Rat	ELISA, IHC-P	1 mg
Biosynth	F502-101970-01	10C-CR1096M1	ACTH antibody	Mouse	Monoclonal	Human; Cross: Reacts with Human and Rat. Specific for Synacthen (1-24 ACTH) and has no cross reaction with CLIP (ACTH 17-39).	ELISA, IHC (paraffin), ICC	0.1 mg
Biosynth	F502-100367-01	10-2353	ACTH antibody	Mouse	Monoclonal	Human	ELISA, RIA, Lateral Flow	0.5 mg
Biosynth	F502-101407-01	10-A31A	ACTH antibody	Mouse	Monoclonal	Human; Cross: Rat	ELISA, IHC-P	1 mg
Cloud-Clone	T813-112541-01	MAA836Hu28	Monoclonal Antibody to Adrenocorticotropic Hormone (ACTH)	Mouse	Monoclonal	Human	Testing in progress	100µl
Cloud-Clone	T813-112540-01	MAA836Hu21	Monoclonal Antibody to Adrenocorticotropic Hormone (ACTH)	Mouse	Monoclonal	Human	WB	100µl
Cloud-Clone	T813-119839-01	PAA836Ca01	Polyclonal Antibody to Adrenocorticotropic Hormone (ACTH)	Rabbit	Polyclonal	Canine	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-119840-01	PAA836Hu08	Polyclonal Antibody to Adrenocorticotropic Hormone (ACTH)	Rabbit	Polyclonal	Human	ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).	100µl
MyBioSource	R247-150796-01	MBS4380173	ACTH (Adrenocorticotrophic Hormone), Monoclonal Antibody	Rabbit	Monoclonal	Human, Mouse, Rat	FC/FACS; IF; Immunohistochemistry (IHC) Formalin	0.02 mg
MyBioSource	R247-192603-01	MBS832282	ACTH, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat, Pig	ELISA; ICC; IHC; WB	0.25 mL
Biosynth	F502-109333-01	20R-2533	ACTH antibody	Rabbit		Reacts with Human and Pig	ELISA, ICC, IHC, WB	250 ul
Biosynth	F502-108049-01	20-AS01	ACTH (1-24) antibody	Sheep		To be determined by end-user	User optimized	100 ul
Biosynth	F502-100698-01	10-2946	ACTH N-Terminal Ab 6Y8	Mouse	Monoclonal	Human, Rat	ELISA, IHC(P)	0.2 mg
Biosynth	F502-100697-01	10-2945	ACTH N-Terminal Ab 6Y8	Mouse	Monoclonal	Human, Rat	ELISA, IHC(P)	0.05 mg, 0.1 mg

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
Cloud-Clone	T813-106437-01	KSA836Mu11	ELISA Kit DIY Materials for Adrenocorticotropic Hormone (ACTH)	Murine	ELISA	Serum, plasma and other biological fluids.	4.38pg/mL	96T*10
Cloud-Clone	T813-106438-01	KSA836Ra11	ELISA Kit DIY Materials for Adrenocorticotropic Hormone (ACTH)	Rat	ELISA	Serum, plasma and other biological fluids.	5.25pg/mL	96T*10
Cloud-Clone	T813-106436-01	KSA836Hu11	ELISA Kit DIY Materials for Adrenocorticotropic Hormone (ACTH)	Human	ELISA	Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.	5.47pg/mL	96T*10
Cusabio	T094-102212-01	CSB-E14322B	Bovine adrenocorticotropic hormone (ACTH) ELISA kit	Bos taurus (Bovine)	ELISA	serum, plasma	3.9 pg/ml	96T,5×96T,10×96T
Cusabio	T094-102598-01	CSB-E18039Hs	Horse adrenocorticotropic hormone (ACTH) ELISA kit	Equus caballus (Horse)	ELISA	serum, plasma	3.9 pg/ml	96T,5×96T,10×96T
Cusabio	T094-100403-01	CSB-E06875r	Rat adrenocorticotropic hormone (ACTH) ELISA kit	Rattus norvegicus (Rat)	ELISA	serum, plasma, tissue homogenates	1.25 pg/mL	96T,5×96T,10×96T
Cusabio	T094-101737-01	CSB-E12944p	Pig adrenocorticotropic hormone (ACTH) ELISA kit	Sus scrofa (Pig)	ELISA	serum, plasma, tissue homogenates	6.25 pg/mL	96T,5×96T,10×96T
Cusabio	T094-102362-01	CSB-E15926Fh	Fish adrenocorticotropic hormone (ACTH) ELISA kit	Fish	ELISA	serum, plasma, tissue homogenates	75 pg/mL	96T,5×96T,10×96T
Cusabio	T094-100401-01	CSB-E06873h	Human adrenocorticotropic hormone (ACTH) ELISA kit	Homo sapiens (Human)	ELISA	serum, plasma, tissue homogenates	12.5 pg/mL	96T,5×96T,10×96T
Cusabio	T094-100402-01	CSB-E06874m	Mouse adrenocorticotropic hormone (ACTH) ELISA kit	Mus musculus (Mouse)	ELISA	serum, plasma	4.68 pg/mL	96T,5×96T,10×96T
Cusabio	T094-102227-01	CSB-E14373C	Chicken adrenocorticotropic hormone (ACTH) ELISA kit	Gallus gallus (Chicken)	ELISA	serum, plasma, tissue homogenates	0.125 pg/mL	96T,5×96T,10×96T
MyBioSource	R247-174628-01	MBS705669	adrenocorticotropic hormone (ACTH), ELISA Kit	Fish	ELISA	Serum, plasma, tissue homogenates	< 75 pg/ml	24-Strip-Wells
MyBioSource	R247-101677-01	MBS022660	Adrenocorticotropic Hormone (ACTH), ELISA Kit	Monkey	ELISA	Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids	1.0 pg/ml.	48-Strip-Wells
MyBioSource	R247-172272-01	MBS700891	adrenocorticotropic hormone	Bovine	ELISA	Serum, plasma	The minimum detectable dose of bovine ACTH is typically less than 0.12 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest bovine ACTH concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.	24-Strip-Wells
MyBioSource	R247-102843-01	MBS035803	Adrenocorticotropic Hormone (ACTH), ELISA Kit	Rat	ELISA	Body fluids, tissue homogenates, secretions or feces samples	1.0 pg/ml.	48-Strip-Wells
MyBioSource	R247-173124-01	MBS703975	adrenocorticotropic hormone (ACTH), ELISA Kit	Chicken	ELISA	Serum, plasma, tissue homogenates	< 0.125 pg/ml	24-Strip-Wells
MyBioSource	R247-172231-01	MBS700745	adrenocorticotropic hormone (ACTH), ELISA Kit	Pig	ELISA	Serum, plasma, tissue homogenates	< 6.25 pg/ml	24-Strip-Wells
MyBioSource	R247-135521-01	MBS2501576	ACTH, ELISA Kit	Porcine	ELISA	Serum, plasma and other biological fluids	9.38pg/mL	24 Tests
MyBioSource	R247-139308-01	MBS260108	Adrenocorticotropic Hormone (ACTH), ELISA Kit	Mouse	ELISA		Up to 5 pg/mL	48-Strip-Wells
MyBioSource	R247-103164-01	MBS039585	Adrenocorticotropic Hormone (ACTH), ELISA Kit	Canine	ELISA		1.0pg/ml	48-Strip-Wells
Cloud-Clone	T813-101095-01	CEA836Cp	ELISA Kit for Adrenocorticotropic Hormone (ACTH)	Caprine	ELISA	Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids	4.92pg/mL.	96T
Cloud-Clone	T813-101094-01	CEA836Ca	ELISA Kit for Adrenocorticotropic Hormone (ACTH)	Canine	ELISA	serum, plasma and other biological fluids	5.06pg/mL.	96T
Cloud-Clone	T813-101097-01	CEA836Mu	ELISA Kit for Adrenocorticotropic Hormone (ACTH)	Murine	ELISA	serum, plasma and other biological fluids	5.78pg/mL.	96T
Cloud-Clone	T813-101096-01	CEA836Hu	ELISA Kit for Adrenocorticotropic Hormone (ACTH)	Human	ELISA	serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids	5.12pg/mL.	96T
Cloud-Clone	T813-101093-01	CEA836Bo	ELISA Kit for Adrenocorticotropic Hormone (ACTH)	Bovine	ELISA	Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids	4.57pg/mL.	96T
Cloud-Clone	T813-101098-01	CEA836Ra	ELISA Kit for Adrenocorticotropic Hormone (ACTH)	Rat	ELISA	serum, plasma and other biological fluids	0.52pg/mL.	96T

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
MyBioSource	R247-124611-01	MBS2001134	Adrenocorticotropic Hormone (ACTH), CLIA Kit	Human	CLIA	Serum, Plasma, Tissue homogenates, Cell lysates, Cell culture supernates and other biological fluids	1.5pg/mL	24-Strip-Wells
Cloud-Clone	T813-100720-01	CCA836Hu	CLIA Kit for Adrenocorticotropic Hormone (ACTH)	Human	CLIA	serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids	1.5pg/mL.	96T
Cloud-Clone	T813-100722-01	CCA836Ra	CLIA Kit for Adrenocorticotropic Hormone (ACTH)	Rat	CLIA	serum, plasma and other biological fluids	4.52pg/mL.	96T
Cloud-Clone	T813-100721-01	CCA836Mu	CLIA Kit for Adrenocorticotropic Hormone (ACTH)	Murine	CLIA	Serum, plasma and other biological fluids	5.12pg/mL.	96T

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