ACAT1 — 카탈로그 16건
Gene ACAT1
NCBI Gene 38
국내 소싱 가능
16건
유전자 개요
이 유전자는 아세틸-CoA 두 분자로부터 아세토아세틸-CoA의 가역적 형성을 촉매하는, 미토콘드리아에 국소화된 효소(enzyme)를 지정합니다. 이 유전자의 결함은 3-케토싸이올레이스 결핍증과 연관되는데, 이는 2-메틸-3-하이드록시뷰티르산, 2-메틸아세토아세트산, 티글릴글리신, 부타논의 소변 배설을 특징으로 하는 이소류신 대사의 선천성 오류입니다.
Beta-ketothiolase deficiencyBranched-chain amino acid catabolismMaturation of TCA enzymes and regulation of TCA cycleMitochondrial protein degradationSynthesis of Ketone BodiesUtilization of Ketone Bodies
beta-ketothiolase deficiencyerythrocyte volumegenetic disordererythrocyte countmean corpuscular hemoglobineosinophil countprotein measurementmean corpuscular hemoglobin concentration
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism. · Nature (2016)TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge. · Neuron (2020)Mechanisms of foam cell formation in atherosclerosis. · J Mol Med (Berl) (2017)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-105333-01 | CSB-PA001134ESR1HU | ACAT1 Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | ELISA, WB, IHC | 50μl, 100μl | |
| Cusabio | T094-105334-01 | CSB-PA001134LA01HU | ACAT1 Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | ELISA, WB, IHC | 50μg, 100μg | |
| Biosynth | F502-125382-01 | 70R-2469 | ACAT1 antibody | Rabbit | Polyclonal | Human,Mouse,Rat | WB | 100 ul | |
| Biosynth | F502-118317-01 | 70R-15534 | ACAT1 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, IF, WB | 50 ul | |
| Biosynth | F502-125381-01 | 70R-2468 | ACAT1 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish | WB | 100 ul | |
| Biosynth | F502-133665-01 | 70R-49325 | ACAT1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of ACAT1 protein; Cross: Mouse, Rat, Monkey | WB, IHC, IP | 100 ul | |
| Biosynth | F502-129271-01 | 70R-33980 | ACAT1 antibody | Rabbit | Polyclonal | ACAT1 antibody detects endogenous levels of total ACAT1 protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-107010-01 | 10R-8652 | ACAT1 antibody | Mouse | Monoclonal | Human | ELISA, WB | 50 ul | |
| Cloud-Clone | T813-125260-01 | PAD664Mu01 | Polyclonal Antibody to Acetyl Coenzyme A Acetyltransferase 1 (ACAT1) | Rabbit | Polyclonal | Murine | WB,ICC/IF | 100µl | |
| Cloud-Clone | T813-125261-01 | PAD664Mu02 | Polyclonal Antibody to Acetyl Coenzyme A Acetyltransferase 1 (ACAT1) | Rabbit | Polyclonal | Murine | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-125259-01 | PAD664Hu01 | KO-Validated Polyclonal Antibody to Acetyl Coenzyme A Acetyltransferase 1 (ACAT1) | Rabbit | Polyclonal | Human | WB; IHC; ICC/IF; FCM | 100µl | |
| ELK Biotechnology | T376-117463-01 | ES1577 | ACAT-1 rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | WB;IHC;IF;ELISA | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
BDH1
Utilization of Ketone Bodies
OXCT1
Utilization of Ketone Bodies
HMGCL
Synthesis of Ketone Bodies
CS
Maturation of TCA enzymes and regulation of TCA cycle
IDH2
Maturation of TCA enzymes and regulation of TCA cycle
ACO2
Maturation of TCA enzymes and regulation of TCA cycle
ACADSB
Branched-chain amino acid catabolism
DLD
Branched-chain amino acid catabolism