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MyBioSource
MBS603390 — Helicobacter pylori Urease, Large Subunit Antigen, Monoclonal Antibody
Target H. pylori produces large amounts of the enzyme urease, molecules of which are localized inside and outside of the bacterium. Urease breaks down urea (which is normally secreted into the stomach) to carbon dioxide and ammonia. The ammonia is converted to ammonium by accepting a proton (H+), which neutralizes gastric acid. The survival of H. pylori in the acidic stomach is dependent on urease. The ammonia produced is toxic to the epithelial cells, and along with the other products of H. pyloriâincluding proteases, vacuolating cytotoxin A (VacA), and certain phospholipases, damages those cells.
Host Mouse
Clonality Monoclonal
Conjugate N/A
Reactivity Recognizes the Urease large subunit in an extract of a cytotoxic H. pylori strai
Assay N/A
Application ELISA; WB
Specifications
| Cat No | R247-159621-01 0.1 mg |
|---|---|
| Mfr No | MBS603390 |
| 제조사 | MyBioSource |
| 제품명 | Helicobacter pylori Urease, Large Subunit Antigen, Monoclonal Antibody |
| Sub type | Primary |
| Target | H. pylori produces large amounts of the enzyme urease, molecules of which are localized inside and outside of the bacterium. Urease breaks down urea (which is normally secreted into the stomach) to carbon dioxide and ammonia. The ammonia is converted to ammonium by accepting a proton (H+), which neutralizes gastric acid. The survival of H. pylori in the acidic stomach is dependent on urease. The ammonia produced is toxic to the epithelial cells, and along with the other products of H. pyloriâincluding proteases, vacuolating cytotoxin A (VacA), and certain phospholipases, damages those cells. |
| Host | Mouse |
| Reactivity | Recognizes the Urease large subunit in an extract of a cytotoxic H. pylori strai |
| Application | ELISA; WB |
| Clonality | Monoclonal |
| 보관 | 4°C |
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