재조합 데스모콜린 3 (Recombinant Desmocollin 3, DSC3)은 세포 접착 및 조직 발달에 중요한 역할을 하는 세포외 기질 단백질입니다. DSC3은 카드헤린 계열에 속하며, 탈단백질화된 세포 표면에서 세포-세포 결합을 매개하고 상피 세포의 구조적 무결성을 유지하는 데 기여합니다. 이 단백질의 비정상적인 발현은 피부 질환, 구강 질환 및 특정 유형의 암과 관련이 있는 것으로 알려져 있습니다. 본 제품은 연구용으로 제공되며, 50µg 규격으로 공급됩니다. Mouse gene_summary: Encodes desmocollin 3, a member of the desmosomal cadherin family. Desmosomes are cadherрите-mediated cell-cell adhesion complexes that are expressed in epithelial tissues. The desmosomal cadherins are transmembrane glycoproteins that contain cadherin family domains. Desmosomes function to organize the epithelial cytoskeleton into a resilient, continuous network that is resistant to mechanical stress. This family of proteins is involved in cell adhesion and signaling pathways that are important for tissue development and homeostasis. Loss of desmosomal function can lead to various skin diseases, such as arrhythmogenic right ventricular dysplasia, dilated cardiomyopathy, and woolly hair syndrome. This protein is part of a gene cluster that is thought to have arisen by duplication of a common ancestral gene. [Note: provided gene_summary is for human, but the product is recombinant. Assuming mouse recombinant protein based on the product code RPG437Mu01. The gene_summary information is relevant to the protein’s function, regardless of species.]
